https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/244 2026-04-04T10:23:41Z 2026-04-04T10:23:41Z Jun, Joon-Hee Chun, Kyung-A Kum, Kee-Yeon Lee, WooCheol Shon, Won-Jun Yoo, Yeon-Jee Baek, Seung-Ho https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/33975 2024-07-12T11:31:02Z 2021-04-01T00:00:00Z

Title: Effect of mineral trioxide aggregate plug location on root development in regenerative endodontic procedure Authors: Jun, Joon-Hee; Chun, Kyung-A; Kum, Kee-Yeon; Lee, WooCheol; Shon, Won-Jun; Yoo, Yeon-Jee; Baek, Seung-Ho Abstract: This retrospective study investigated the effect of mineral trioxide aggregate (MTA) plug location on treatment outcome and root maturation after regenerative endodontic procedures (REP) in immature permanent teeth. Thirty-three roots (n = 33) in cohort that underwent REP consistently according to AAE guideline were included to trace radiographic changes for the root and canal dimensions. Based on intraoral radiographs, roots were divided into two groups depending on the location of MTA plug within whole root length: coronal group (n = 14), within the upper half; apical group (n = 19), within the lower half. Periapical radiographs were standardized to assess treatment outcomes and root maturation including root development stages and digital measurements on the change ratios of root length, apex width, radiographic root area (RRA), modified RRA (mRRA), and periapical rarefaction area. The data were statistically analysed using the Mann-Whitney test. The patients' average age was 11 years and 10 months, with no significant between-group difference in sex. Premolars were the most prevalent tooth type (62.1%), followed by incisiors and molars. Pre-existing symptoms and signs subsided within 6 months in all cases. The teeth showed similar radiographic root development in both groups (P > 0.05). However, mRRA increase ratio was significantly higher in apical group than that in coronal group at early (< 6 months) and late (< 24 months) periods of follow-up (P < 0.05). Significant changes of root development stage were observed at early period for apical group and at late period for coronal group (P < 0.05). All the observed cases showed continuing root development after REP. Significant changes in root developments occurred at different follow-up periods according to the location of MTA plugs.

2021-04-01T00:00:00Z Shin, Joo-Hee Ryu, Jae Jun Lee, Sung-Hoon https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/49198 2025-09-15T04:30:48Z 2021-01-01T00:00:00Z

Title: Antimicrobial activity and biocompatibility of the mixture of mineral trioxide aggregate and nitric oxide-releasing compound Authors: Shin, Joo-Hee; Ryu, Jae Jun; Lee, Sung-Hoon Abstract: Background/purpose: Antimicrobial activity and biocompatibility of root canal sealer are related to the success of endodontic treatments. This study investigated the efficacy of mixture of mineral trioxide aggregate (MTA) and a NO-releasing compound for the antimicrobial activity, biocompatibility, and physical properties. Materials and methods: MTA was mixed with diethylenetriamine-NO (MTA-NO), and the extracts from MTA and the MTA-NO mixture before and after setting was obtained were investigated the antimicrobial activity against Enterococcus faecalis and Porphyromonas endodontalis. After setting MTA and MTA-NO, pulp cell was incubated in the presence of MTA and MTA-NO disk using Transwell (R) cell culture insert, and the proliferation assay and mineralization-stimulated factors of the cells were analyzed by MTT assay and real-time RT-PCR, respectively. The physical properties of MTA and the MTA-NO mixture, such as surface hardness and flowability was also analyzed. Results: The MTA-NO mixture showed stronger antimicrobial activity against E. faecalis and P. endodontalis than that by MTA. Both MTA and MTA-NO mixture increase the ratio of cell proliferation and induced the expression of alkaline phosphatase, collagen type I, osteocalcin, and osteopontin. Moreover, the induction of gene expression by MTA-NO mixture was higher than that by MTA alone. No significant difference was observed for surface hardness and flowability between MTA and MTA-NO mixture. Conclusion: The addition of a NO-releasing compound to the endodontic treatment using MTA root canal sealer might reduce the risk of bacterial infection and help to regenerate the dental pulp tissue. (C) 2020 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V.

2021-01-01T00:00:00Z 정홍택 Shiela A. Campana 박진홍 신주희 이정열 https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/28869 2023-12-19T20:04:58Z 2019-04-01T00:00:00Z

Title: 레진 시멘트와 코발트 크롬 합금의 미세인장결합강도에 다양한 프라이머들이 미치는 영향 Authors: 정홍택; Shiela A. Campana; 박진홍; 신주희; 이정열 Abstract: Purpose: The aim of this study is to evaluate the effects of various primers on the microtensile bond strength (μTBS) of resin cements to cobalt-chromium (Co-Cr) dental casting alloy. Materials and methods: Four adhesive primers (Universal primer, Metal primer II, Alloy primer, and Metal/Zirconia primer) and two resin cements (Panavia F2.0, G-CEM LinkAce) were tested. One hundred fifty Co-Cr beams were prepared from Co-Cr ingots via casting (6 mm length × 1 mm width × 1 mm thick). The metal beams were randomly divided into ten groups according to the adhesive primers and resin cements used; the no-primer groups served as the control (n = 15). After sandblasting with aluminum oxide (125 μm grain), the metal and resin cements were bonded together using a silicone mold. Prior to testing, all metal-resin beams were examined under stereomicroscope, and subjected to the μTBS test. The mean value of each group was analyzed via one-way ANOVA with Tukey’s test as post hoc (α = .05) using SPSS software. Results: The mean μTBS of all groups was ranged from 20 to 28 MPa. There is no statistically significant difference between groups (P > .05). Mixed failure, which is the combination of adhesive and cohesive failures, is the most prevalent failure mode in both the Panavia F2.0 and G-Cem LinkAce groups. Conclusion: The μTBS of all tested groups are relatively high; however, the primers used in this study result in no favorable effect in the μTBS of Panavia F2.0 and G-Cem LinkAce resin cement to Co-Cr alloy.

2019-04-01T00:00:00Z Chung, Shin Hye Chun, Kyung A. Kim, Hae-Young Kim, Young-Sun Chang, Juhea https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/28788 2024-07-13T01:30:41Z 2019-02-01T00:00:00Z

Title: Periapical Healing in Single-visit Endodontics under General Anesthesia in Special Needs Patients Authors: Chung, Shin Hye; Chun, Kyung A.; Kim, Hae-Young; Kim, Young-Sun; Chang, Juhea Abstract: Introduction: The aim of this study was to determine the prognostic factors of periapical healing of teeth after singlevisit nonsurgical endodontic treatment under general anesthesia in special needs patients. Methods: This retrospective study collected 448 teeth from 241 patients (mean age = 27.4 years, standard deviation = 13.9 years). A total of 271 teeth (60.5%) with clinical and radiographic follow-up records longer than 12 months (mean [standard deviation] = 56.1 [27.9]) were included in the outcome analysis. Demographic, systemic, and dental information about the cases were compared between the healed and nonhealed groups using the Pearson chi-square test. Factors contributing to periapical healing were determined with multivariate logistic regression analysis. Results: Complete periapical healing without clinical signs was observed in 221 teeth (81.5%), uncertain healing with decreased size of the periapical lesion was shown in 43 teeth (15.9%), and no reduction in lesion size was observed in 7 cases (2.6%). In the multivariate analysis, diet type, oral hygiene maintenance, pulp vitality, and root filling length were detected as contributing factors for complete resolution of periapical lesions (P <.05). Conclusions: Successful outcomes of singlevisit endodontic treatment under general anesthesia were shown in special needs patients. The prognoses were influenced by the clinical circumstances of the patients and the preoperative conditions of their teeth.

2019-02-01T00:00:00Z