https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/636 2026-04-04T14:16:26Z 2026-04-04T14:16:26Z Shim, K. Yun, Y. Kim, S. Song, H. https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/49475 2023-12-14T04:01:54Z 20141201-01-01T00:00:00Z

Title: The Effect of Alendronate-Loaded Polycarprolactone Nanofibrous Scaffolds on Osteogenic Differentiation of Adipose-Derived Stem Cells in Bone Tissue Regeneration Authors: Shim, K.; Yun, Y.; Kim, S.; Song, H.

20141201-01-01T00:00:00Z Lee, J. Yun, Y. Kim, S. Song, H. https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/49476 2023-12-14T04:01:54Z 20141201-01-01T00:00:00Z

Title: Osteogenesis Induction of Periodontal Ligament Cells onto Bone Morphogenic Protein-2 Immobilized PCL Fibers Authors: Lee, J.; Yun, Y.; Kim, S.; Song, H.

20141201-01-01T00:00:00Z Kim S.E. Lee S.-Y. Yun Y.-P. Lee J.Y. Park K. Lee D.-W. Song H.-R. https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/43613 2023-12-14T03:31:46Z 201210-01-01T00:00:00Z

Title: The effect of an alendronate-eluting titanium system to induce osteogenic differentiation in human buccal fat cells (HBFCs) Authors: Kim S.E.; Lee S.-Y.; Yun Y.-P.; Lee J.Y.; Park K.; Lee D.-W.; Song H.-R. Abstract: The purpose of this study was to develop alendronate (Aln)-eluting Ti substrates to induce osteogenic differentiation of human buccal fat cells (HBFCs). The surface of pristine Ti was modified by dopamine (DOPA) and then heparin was grafted onto the aminated Ti surfaces to achieve the Aln-eluting Ti system. Aln was subsequently immobilized on the surface of heparinized Ti (Hep-Ti). Pristine Ti and surface-modified-Ti were characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and contact angle. Osteogenic differentiation of HBFCs on the surface of pristine-Ti, Hep-Ti, Aln (1 mg)/Hep-Ti, and Aln (5 mg)/Hep-Ti was demonstrated by alkaline phosphatase (ALP) activity, calcium deposition, and osteocalcin and osteopontin mRNA expression. Successful immobilization of Aln on Hep-Ti was confirmed by XPS and contact angle. Aln/Hep-Ti showed the sustained release for up to 28 days. Additionally, HBFCs cultured on Aln/Hep-Ti substrates showed significantly induced ALP activity, calcium deposition, and osteocalcin and osteopontin mRNA expression. These results suggest that Aln-eluting Ti substrates have a potential effect on osteogenic differentiation of HBFCs and will be a promising material for bone regeneration. © 2012 SPIE.

201210-01-01T00:00:00Z 송해룡[송해룡] 심규식[심규식] 이재용[이재용] 김학준[김학준] 김성은[김성은] https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/44731 2023-12-14T03:32:24Z

Title: 연부조직 질환 치료용 약물이 탑재된 나노입자가 함유된 줄기세포의 3차원 세포 집합체 및 이의 제조방법 Authors: 송해룡[송해룡]; 심규식[심규식]; 이재용[이재용]; 김학준[김학준]; 김성은[김성은]