https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/654 2026-04-09T04:31:13Z 2026-04-09T04:31:13Z Kim, Junhyung Jeong, Hyun-Ghang Lee, Moon -Soo Pae, Chi-Un Patkar, Ashwin A. Jeon, Sang Won Shin, Cheolmin Han, Changsu https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/66454 2025-10-05T12:39:22Z 2024-05-01T00:00:00Z

Title: Effect of Frailty on Depression among Patients with Late-life Depression: A Test of Anger, Anxiety, and Resilience as Mediators Authors: Kim, Junhyung; Jeong, Hyun-Ghang; Lee, Moon -Soo; Pae, Chi-Un; Patkar, Ashwin A.; Jeon, Sang Won; Shin, Cheolmin; Han, Changsu Abstract: Objective: While the association between depression and frailty in the elderly population has been investigated, the psychological factors that mediate such a relationship remain unknown. The identification of psychological factors in interventions for depression treatment in the elderly may assist in the treatment and care. We aimed to explore the mediating effects of anger, anxiety, and resilience on the link between frailty and depression symptoms in patients with late -life depression. Methods: A sample of 203 older adults completed questionnaires that assessed depression, anger, resilience, and anxiety. To measure frailty, participants were evaluated using a self -rated health questionnaire, weight -adjusted waist index related to sarcopenia, and weight -adjusted handgrip strength to evaluate weakness. A mediation model was tested, hypothesizing that anger, anxiety, and resilience would partially mediate the strength of the frailty -depression link in the elderly. Results: Only self -rated health showed a significant association with depressive symptoms in late -life depression. Our study demonstrated that frailty has both direct and indirect associations with depression, mediated by anger, resilience, and anxiety. Conclusion: Given that anger, resilience, and anxiety influence the link between self -rated health and depression, interventions that lead to increased resilience and decreased anger and anxiety may be promising to reduce depressive symptoms in older adults with depression.

2024-05-01T00:00:00Z Kim, Hesun Erin Eom, Hyojung Jo, Hye-Jeong Kim, Min-Kyeong Kim, Junhyung Kim, Jae-Jin https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/66458 2024-07-11T10:00:18Z 2024-03-01T00:00:00Z

Title: Neural substrates of marriage on self-parents processing and the association with a parents-oriented perspective shift in a collectivistic culture Authors: Kim, Hesun Erin; Eom, Hyojung; Jo, Hye-Jeong; Kim, Min-Kyeong; Kim, Junhyung; Kim, Jae-Jin Abstract: Relationship with parents is a special bond that shapes self-other representations and have an impact on adultchild's marriage, especially in the early stages of marriage. This study sought to investigate the neural mechanisms underlying self-parents processing as well as their relationship with marriage. Seventy-eight premarital Korean participants were scanned in functional MRI while evaluating traits of the self and parents. Then, 21 of them returned after being married to engage in the identical task three years later. The precuneus and temporoparietal junction were identified to activate stronger for parents than self at both marital statuses. The dorsal anterior cingulate cortex, posterior cingulate cortex, parietal operculum, and caudate activated more for self than parents before marriage, but their activities changed during marriage. The activation increase of the parietal operculum between marital statuses in the parents condition was negatively correlated with the level of marital dissatisfaction, and this association only appeared among participants with a child. Self-parents processing may recruit brain regions involved in autobiographical memory and self-other distinction, and marriage has an impact on the way individuals process rewards and multimodal sensory information during this processing. Marriage may lead to changes in brain function that affect the processing of emotions toward parents and a more parents-oriented perspective shift in collectivistic societies.

2024-03-01T00:00:00Z Kim, J. Kim, S. H. https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/64538 2024-01-11T02:00:07Z 202303-01-01T00:00:00Z

Title: Relationship of smartphone use severity with sleep quality in bipolar patients Authors: Kim, J.; Kim, S. H. Abstract: Introduction Maintaining a good sleep-wake cycle is an important factor for the prognosis and management of bipolar disorder. However, studies on the to various technological advances including smartphoe usage affecting inter-episodic sleep quality are yet relatively less thoroughly investigated. Objectives This study aims to identify the association between smartphone usage and inter-episodic sleep quality of bipolar patients. Methods A total 52 Bipolar I or II subjects who were euthymic for at lest 6 months were included in this analysis. Pearson correlation analysis was used to examine the association among psychological assessments, including the Pittsburgh Sleep Quality Index (PSQI-K), Smartphone Addiction Scale (SAS), Hamilton Depression Rating Scale (K-HDRS), Young Mania Rating Scale (K-YMRS), and Multidimensional Scale of Perceived Social Support (MDPSS). Significant results were then analyzed using a multiple linear regression analysis with PSQI-K as the dependent variable to assess the impact of clinical variables on sleep quality. Results PSQI-K was positively correlated with SAS (r = 0.457, p < 0.001), K-HDRS (r = 0.447, p < 0.001), and negatively correlated with MDPSS (r = -0.336, p < 0.05). Smartphone use, depressive symptoms, and perceived social support seemed to explain 35.7% of sleep quality. After adjusting for confounders, more smartphone use and more severe depressive symptoms were associated with poor sleep quality (SAS: β = 0.383, p = 0.002; K-HDRS: β = 0.339, p = 0.006), but perceived social support did not reach statistical significance (MDPSS: β = -0.204, p = 0.086). Conclusions The results of this study show that the more a person uses a smartphone, the worse their sleep is. This effect is significant, even when other factors are taken into account. These results support the possibility that improving the degree of smartphone use could be an essential intervention target for improving sleep quality during the inter-episode period in patients with bipolar disorder.

202303-01-01T00:00:00Z Seo, Surin Hyung, Won Seok William Lee, Seung-Hoon Kim, Junhyung Choi, Kwang-Yeon Youn, HyunChul Jeong, Hyun-Ghang https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/64841 2024-07-11T10:30:46Z 2023-10-01T00:00:00Z

Title: Influence of Anesthesia on Incidence of Dementias: 8-Year Follow-Up Study Authors: Seo, Surin; Hyung, Won Seok William; Lee, Seung-Hoon; Kim, Junhyung; Choi, Kwang-Yeon; Youn, HyunChul; Jeong, Hyun-Ghang Abstract: <jats:p>Objective: Cognitive dysfunction is frequently reported after surgery and anesthesia in elderly patients. This study aims to investigate the incidence of dementia for eight years after anesthesia.
 Methods: We extracted the data between 2007 and 2020 from the Health Insurance Review and Assessment Service Database. We analyzed risk of developing dementia after anesthesia using Cox proportional hazard models.
 Results: Data were collected from 62,541 patient. Among them, subjects with and without anesthesia were 15,857 and 46,684, respectively. Subjects with anesthesia had more hypertension, diabetes mellitus and hyperlipemia than those without anesthesia. The risk of dementia incidence was found to increase 1.7 times in subjects with anesthesia (hazard ratio=1.751, 95% confidence interval=1.596-1.921). Even after the correction for gender, age, and comorbidity, the statistical significance of this risk remained (hazard ratio=1.662, 95% confidence interval=1.512-1.827).
 Conclusion: Our findings suggest that anesthesia possibly contribute on cognitive impairment. Clinician might need closed observation on cognitive function in patients after surgery and anesthesia.</jats:p>

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