https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/280 Sat, 04 Apr 2026 09:03:09 GMT 2026-04-04T09:03:09Z https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/64127 Title: Unravelling interobserver variability in gastrointestinal glandular neoplasia: a contemporary study of US and Korean pathologists Authors: Pacheco, Richard R.; Kim, Hyunki; Choi, Won-Tak; Kook, Myeong-Cherl; Cho, Mee-Yon; Karamchandani, Dipti M.; Lee, Michael J.; Kim, Baek-Hui; Lee, Sung-Hak; Yang, Zhaohai; Kim, Jihun; Lagana, Stephen M.; Lee, Hwajeong Abstract: AimsInterobserver variability in the assessment of gastric neoplasia biopsies between most Western and Eastern (predominantly represented by Japanese in the literature) pathologists has been documented. It is unknown if such variability exists between the US and Korean pathologists in the current era.MethodsTen gastrointestinal (GI) pathologists from the USA (n=5) and South Korea (n=5) evaluated 100 scanned images of gastric (n=50) and colorectal (n=50) neoplasia biopsies and answered multiple questionnaires. Consensus was defined as the answer chosen by the majority. Cohen's (& kappa;c) and Fleiss' kappa (& kappa;f) values were calculated between the consensus of the two groups and among the raters, respectively.ResultsBoth groups reached a consensus in the majority of cases (74%-100%) with slight to perfect intergroup (& kappa;c=0.049-1.000) and no to substantial intragroup (& kappa;f=-0.083 to 0.660) agreements. For gastric neoplasia, Korean pathologists relied heavily on cytoarchitectural atypia, whereas the US pathologists focused on stromal invasion when diagnosing adenocarcinoma. For colorectal neoplasia, the Korean pathologists identified concurrent intramucosal carcinoma when diagnosing invasive adenocarcinoma, while the presence of desmoplasia was a prerequisite for the diagnosis of invasive adenocarcinoma for the US pathologists.ConclusionsFor GI neoplasia biopsy interpretation, the diagnostic approach of Korean pathologists is similar to that of Eastern/Japanese pathologists. Consensus outperformed kappa statistics in capturing the magnitude of inter-rater and intergroup reliability, highlighting the potential benefit of consensus meetings to decrease the gap between Western and Eastern diagnostic approaches. Sun, 01 Dec 2024 00:00:00 GMT https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/64127 2024-12-01T00:00:00Z https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/63600 Title: Should Cystic Duct Cancer Be Considered as Gallbladder Cancer, Distal Extrahepatic Bile Duct Cancer, or The Third Party Cancer? Authors: Kim, Yeseul; Jung, Haesung; Sung, You-Na; Jun, Sun-Young; Cho, HyungJun; Hong, Seung-Mo Sun, 01 Jan 20230311 00:00:00 GMT https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/63600 20230311-01-01T00:00:00Z https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/63601 Title: MAML2 Rearrangements in Different Tumor Locations and Variant Forms of Mucoepidermoid Carcinoma Authors: Kim, Yeseul; Sung, You-Na; Nam, Soon Yuhl; Cho, Kyung-Ja Sun, 01 Jan 20230311 00:00:00 GMT https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/63601 20230311-01-01T00:00:00Z https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/63603 Title: Interobserver Variability Between United States and Korean Pathologists' Interpretation of Colorectal and Gastric Cancer Biopsies: Can We Reach a Consensus? Authors: Pacheco, Richard R.; Kim, Hyunki; Kook, Myeong-Cherl; Choi, Won-Tak; Kim, Baek-Hui; Karamchandani, Dipti; Yang, Zhaohai; Cho, Mee-Yon; Lee, Sung Hak; Lee, Michael; Kim, Jihun; Lagana, Stephen; Lee, Jenny Hwajeong Sun, 01 Jan 20230311 00:00:00 GMT https://scholarworks.korea.ac.kr/kumedicine/handle/2021.sw.kumedicine/63603 20230311-01-01T00:00:00Z