Clinical evaluation of the computerized Chronic Urticaria-Specific Quality of Life questionnaire in Korean patients with chronic urticaria
- Authors
- Ye, Y. -M.; Park, J. -W.; Kim, S. -H.; Choi, J. -H.; Hur, G. -Y.; Lee, H. -Y.; Lee, E. -H.; Park, H. -S.
- Issue Date
- Oct-2012
- Publisher
- WILEY
- Keywords
- Gastric cancer; Second-line therapy; Asian patients; Ixabepilone
- Citation
- CLINICAL AND EXPERIMENTAL DERMATOLOGY, v.37, no.7, pp 722 - 728
- Pages
- 7
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- CLINICAL AND EXPERIMENTAL DERMATOLOGY
- Volume
- 37
- Number
- 7
- Start Page
- 722
- End Page
- 728
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/11709
- DOI
- 10.1111/j.1365-2230.2012.04414.x
- ISSN
- 0307-6938
1365-2230
- Abstract
- Background. Chronic urticaria (CU) is a common skin disorder that affects the well-being and quality of life (QOL) of patients. Recently, we developed and validated a questionnaire for measuring QOL in Korean patients with CU, called the Chronic Urticaria-Specific Quality of Life (CU-QOL) questionnaire. Aim. To evaluate the clinical significance of a computerized version of the CU-QOL, in adult patients with CU. Methods. This was a cross-sectional observational study that enrolled 249 Korean patients with CU from five university hospitals and measured computerized CU-QOL scores and Urticaria Activity Score (UAS) simultaneously. The internal consistency of the computerized CU-QOL was analysed using Cronbach a. To identify clinical correlations between the CU-QOL and patient characteristics, the atopic status and serum autoantibodies, including antinuclear, antithyroglobulin and antimicrosome antibodies, were measured. Multiple linear regression models were used to identify CU-QOL predictors. Results. Cronbach a was 0.94 for the overall computerized CU-QOL score. The CU-QOL scores correlated significantly with the UAS (r = -0.49, P < 0.001). Of the factors aggravating CU, delayed pressure, sunlight exposure and emotional stress significantly influenced the overall CU-QOL scores in the univariate analysis. Multivariate regression models indicated that UAS and emotional stress were significant predictors of the four domains and of the total CU-QOL scores. Conclusions. The computerized CU-QOL is a convenient and valid tool for measuring QOL in patients with CU. This study suggests that UAS, dermatographism and emotional stress are strong CU-QOL predictors in Korean patients with CU.
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- Appears in
Collections - 2. Clinical Science > Department of Pulmonary, Allergy, and Critical Care Medicine > 1. Journal Articles
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