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Cited 23 time in webofscience Cited 25 time in scopus
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Bright light therapy as an adjunctive treatment with risperidone in patients with delirium: a randomized, open, parallel group study

Authors
Yang, JaewonChoi, WonseokKo, Young-HoonJoe, Sook-HaengHan, ChangsuKim, Yong-Ku
Issue Date
Sep-2012
Publisher
ELSEVIER SCIENCE INC
Keywords
Adjunctive treatment; Delirium; Light therapy; Sleep efficiency; Total sleep time
Citation
GENERAL HOSPITAL PSYCHIATRY, v.34, no.5, pp.546 - 551
Indexed
SCIE
SSCI
SCOPUS
Journal Title
GENERAL HOSPITAL PSYCHIATRY
Volume
34
Number
5
Start Page
546
End Page
551
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/11811
DOI
10.1016/j.genhosppsych.2012.05.003
ISSN
0163-8343
Abstract
Objective: The purpose of this study was to determine the effect of adjuvant light therapy with antipsychotic treatment in patients with delirium. Methods: Thirty-six patients were referred to the consulting psychiatry division of our hospital for a disturbance in consciousness. The patients were randomized to risperidone (n=16) or risperidone with light therapy (n=20). They were evaluated on Day 0 (baseline) and on Days 1 to 5 with the Delirium Rating Scale (DRS) and the Memorial Delirium Assessment Scale (MDAS). Sleep parameters were measured using a sleep log. Results: Mean DRS and MDAS scores decreased significantly over time in both treatment groups. Risperidone with light therapy group showed a significantly greater decrease in the DRS score than the risperidone-only group (F=2.87, P=.025), but the MDAS score was not significantly different between the two groups. There was a significant improvement in total sleep time (F=2.07, P=.037) and sleep efficiency (F=2.79, P=.029) in the risperidone with light therapy group than in the risperidone-only group. Conclusions: Our results indicate that risperidone with light therapy may be a helpful adjuvant treatment for patients with delirium. Adequately powered studies with a head-to-head comparison design are mandatory to confirm our findings. (C) 2012 Elsevier Inc. All rights reserved.
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안산병원 (Department of Psychiatry, Ansan Hospital)
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