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Bright light therapy as an adjunctive treatment with risperidone in patients with delirium: a randomized, open, parallel group study

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dc.contributor.authorYang, Jaewon-
dc.contributor.authorChoi, Wonseok-
dc.contributor.authorKo, Young-Hoon-
dc.contributor.authorJoe, Sook-Haeng-
dc.contributor.authorHan, Changsu-
dc.contributor.authorKim, Yong-Ku-
dc.date.available2020-11-02T23:44:22Z-
dc.date.issued2012-09-
dc.identifier.issn0163-8343-
dc.identifier.issn1873-7714-
dc.identifier.urihttps://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/11811-
dc.description.abstractObjective: The purpose of this study was to determine the effect of adjuvant light therapy with antipsychotic treatment in patients with delirium. Methods: Thirty-six patients were referred to the consulting psychiatry division of our hospital for a disturbance in consciousness. The patients were randomized to risperidone (n=16) or risperidone with light therapy (n=20). They were evaluated on Day 0 (baseline) and on Days 1 to 5 with the Delirium Rating Scale (DRS) and the Memorial Delirium Assessment Scale (MDAS). Sleep parameters were measured using a sleep log. Results: Mean DRS and MDAS scores decreased significantly over time in both treatment groups. Risperidone with light therapy group showed a significantly greater decrease in the DRS score than the risperidone-only group (F=2.87, P=.025), but the MDAS score was not significantly different between the two groups. There was a significant improvement in total sleep time (F=2.07, P=.037) and sleep efficiency (F=2.79, P=.029) in the risperidone with light therapy group than in the risperidone-only group. Conclusions: Our results indicate that risperidone with light therapy may be a helpful adjuvant treatment for patients with delirium. Adequately powered studies with a head-to-head comparison design are mandatory to confirm our findings. (C) 2012 Elsevier Inc. All rights reserved.-
dc.format.extent6-
dc.language영어-
dc.language.isoENG-
dc.publisherELSEVIER SCIENCE INC-
dc.titleBright light therapy as an adjunctive treatment with risperidone in patients with delirium: a randomized, open, parallel group study-
dc.typeArticle-
dc.publisher.location미국-
dc.identifier.doi10.1016/j.genhosppsych.2012.05.003-
dc.identifier.scopusid2-s2.0-84865369427-
dc.identifier.wosid000308511500015-
dc.identifier.bibliographicCitationGENERAL HOSPITAL PSYCHIATRY, v.34, no.5, pp 546 - 551-
dc.citation.titleGENERAL HOSPITAL PSYCHIATRY-
dc.citation.volume34-
dc.citation.number5-
dc.citation.startPage546-
dc.citation.endPage551-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClasssci-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassssci-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaPsychiatry-
dc.relation.journalWebOfScienceCategoryPsychiatry-
dc.subject.keywordPlusINTENSIVE-CARE-UNIT-
dc.subject.keywordPlusMECHANICALLY VENTILATED PATIENTS-
dc.subject.keywordPlusSEASONAL AFFECTIVE-DISORDER-
dc.subject.keywordPlusPOSTOPERATIVE DELIRIUM-
dc.subject.keywordPlusSLEEP DISRUPTION-
dc.subject.keywordPlusASSESSMENT SCALE-
dc.subject.keywordPlusCANCER-PATIENTS-
dc.subject.keywordPlusRATING-SCALE-
dc.subject.keywordPlusMELATONIN-
dc.subject.keywordPlusPREVENTION-
dc.subject.keywordAuthorAdjunctive treatment-
dc.subject.keywordAuthorDelirium-
dc.subject.keywordAuthorLight therapy-
dc.subject.keywordAuthorSleep efficiency-
dc.subject.keywordAuthorTotal sleep time-
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