Detailed Information

Cited 18 time in webofscience Cited 19 time in scopus
Metadata Downloads

Incidence and 30-day mortality of peptic ulcer bleeding in Korea

Authors
Bae, SeungJinKim, NayoungKang, Jung MookKim, Dong-SookKim, Kyoung-MinCho, Yu KyungKim, Jie-HyunJung, Sung WooShim, Ki-Nam
Issue Date
Jun-2012
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Keywords
bleeding; incidence; mortality; peptic ulcer
Citation
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, v.24, no.6, pp 675 - 682
Pages
8
Indexed
SCIE
SCOPUS
Journal Title
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Volume
24
Number
6
Start Page
675
End Page
682
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/12055
DOI
10.1097/MEG.0b013e3283525a56
ISSN
0954-691X
1473-5687
Abstract
Objectives To estimate the rates of peptic ulcer bleeding (PUB) incidence and the association of demographic factors with 30-day mortality after PUB. Methods Diagnostic algorithms for PUB were derived and validated on the basis of 115 true PUB patients at one tertiary hospital in 2005, followed by estimation of age-specific PUB incidence and 30-day mortality rates, using the Korean National Health Insurance claim database. A Cox proportional hazard model was used to determine the impact of demographic factors on the 30-day mortality rate ratio (MRR) after PUB. Results The diagnostic algorithm showed 89 and 88% positive predictive value and sensitivity, respectively. On the basis of this algorithm, the rate of PUB incidence was 22.1 per 100 000 during 2006-2007 and the age-specific incidence rate increased with advanced age. This incidence rate was more than three times higher among men than women. Among 21 107 PUB patients, the overall 30-day mortality rate was 2.15%, but it ranged from 0.83% for patients younger than 60 years to 7.65% for patients older than 80 years. The adjusted 30-day mortality rate ratio for patients older than 80 was 8.13 (95% confidence interval 6.10-10.8) compared with those younger than 60 and 7.09 (95% confidence interval 2.78-4.51) for patients with a high level of comorbidity compared with a low level of comorbidity. Conclusion PUB incidence was higher among men and increased with advanced age. Increased 30-day mortality was observed in association with increasing age, after adjusting for comorbidity. Eur J Gastroenterol Hepatol 24: 675-682 (C) 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins.
Files in This Item
There are no files associated with this item.
Appears in
Collections
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Jung, Sung Woo photo

Jung, Sung Woo
Ansan Hospital (Department of Gastroenterology and Hepatology, Ansan Hospital)
Read more

Altmetrics

Total Views & Downloads

BROWSE