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Cited 4 time in webofscience Cited 6 time in scopus
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Recurrence rates and factors for recurrence after radiofrequency ablation combined with transarterial chemoembolization for hepatocellular carcinoma: a retrospective cohort study

Authors
Kim, Jeong HanYim, Hyung JoonLee, Kwang GyunKim, Seung YoungJung, Eun SukJung, Young KulKim, Ji HoonSeo, Yeon SeokYeon, Jong EunLee, Hong SikUm, Soon HoByun, Kwan SooRyu, Ho Sang
Issue Date
Apr-2012
Publisher
Springer Pub. Co.
Keywords
Hepatocellular carcinoma; Radiofrequency ablation; Transarterial chemoembolization
Citation
Hepatology International, v.6, no.2, pp 505 - 510
Pages
6
Indexed
SCIE
SCOPUS
Journal Title
Hepatology International
Volume
6
Number
2
Start Page
505
End Page
510
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/12271
DOI
10.1007/s12072-011-9290-y
ISSN
1936-0533
1936-0541
Abstract
Purpose There have been reports that radiofrequency ablation (RFA) combined with transarterial chemoembolization (TACE) is as equally effective as surgical resection for the treatment of hepatocellular carcinoma (HCC). This study aimed to evaluate recurrence rate and risk factor of recurrence after RFA combined with TACE for early stage HCC. Methods We reviewed the medical records of the patients who were diagnosed with early stage HCC between March 2006 and August 2008 at Korea University Medical Center and treated with RFA combined with TACE for curative intent (n = 65). Results Recurrence rate was 40% (26 cases) and the time to recurrence was 14.9 months. Cumulative recurrence rate at 1 year was 20% (13 cases) and at 2 years was 33.8% (22 cases). Significant variables for recurrence were: (1) RFA repeated more than one session at initial therapy (P < 0.001) and (2) size of main lesion ≥2 cm (P = 0.047). Conclusions The recurrence rate of combination therapy was considerably high. Regardless of the therapy used, careful post-RFA follow-up is needed, especially if additional treatment is required after the first session or if the main lesion is ≥2 cm at the time of RFA.
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2. Clinical Science > Department of Internal Medicine > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

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Yeon, Jong Eun
Guro Hospital (Department of Gastroenterology and Hepatology, Guro Hospital)
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