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Ceria nanoparticles that can protect against ischemic stroke
- Authors
- Kim C.K.; Kim T.; Choi I.-Y.; Soh M.; Kim D.; Kim Y.-J.; Jang H.; Yang H.-S.; Kim J.Y.; Park H.-K.; Park S.P.; Park S.; Yu T.; Yoon B.-W.; Lee S.-H.; Hyeon T.
- Issue Date
- 2012
- Keywords
- apoptosis; ceria nanoparticles; ischemic stroke; reactive oxygen species; therapeutic agents
- Citation
- Angewandte Chemie - International Edition, v.51, no.44, pp 11039 - 11043
- Pages
- 5
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- Angewandte Chemie - International Edition
- Volume
- 51
- Number
- 44
- Start Page
- 11039
- End Page
- 11043
- ISSN
- 1433-7851
1521-3773
- Abstract
- Uniform 3 nm-sized ceria nanoparticles can protect against ischemic stroke by scavenging reactive oxygen species (ROS) and reducing apoptosis. PEGylated ceria nanoparticles showed protective effects against ROS-induced cell death in vitro. Optimal doses of ceria nanoparticles reduced infarct volumes and the rate of ischemic cell death in vivo. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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Collections - 2. Clinical Science > Department of Neurology > 1. Journal Articles
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Related Researcher
- Kim, Chi Kyung
- Guro Hospital (Department of Neurology, Guro Hospital)