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Cited 6 time in webofscience Cited 8 time in scopus
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Association of sedative-hypnotic medications with suicidality

Authors
Pae, Chi-UnKoh, Jun SungLee, Soo-JungHan, ChangsuPatkar, Ashwin A.Masand, Prakash S.
Issue Date
Mar-2011
Publisher
Future Drugs Ltd.
Keywords
comorbidity; predictor; risk; sedative-hypnotics; suicide
Citation
Expert Review of Neurotherapeutics, v.11, no.3, pp 345 - 349
Pages
5
Indexed
SCIE
SCOPUS
Journal Title
Expert Review of Neurotherapeutics
Volume
11
Number
3
Start Page
345
End Page
349
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/13678
DOI
10.1586/ERN.11.9
ISSN
1473-7175
1744-8360
Abstract
Several studies have investigated the association between sedative-hypnotics and suicidality, as such medications not only serve as a method for suicide, but are also involved in the usual options for treating psychiatric and medico-surgical disorders. According to population-based studies in Europe, Asia and the USA, sedative-hypnotic medications were significantly associated with suicide. However, these studies failed to address psychiatric comorbidities, new hypnotic medications, such as zolpidem, and the specific times at which such medications were used. Recently, Brower and colleagues have investigated the association of the prescription of sedative-hypnotic drugs with suicidality, to determine whether such medications were associated with suicidal ideation, suicide plans and suicide attempts in a large-cohort sample. They found that the use of sedative-hypnotic medications was significantly associated with suicidal ideation, suicide plans and suicide attempts. In addition, the use of sedative-hypnotic medications was a stronger predictor than insomnia of both suicidal ideation and suicide attempts. This article will discuss the relationship between prescription of sedative-hypnotic medications and suicide in the context of the potential limitations and significance of this recent research.
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Han, Changsu
Ansan Hospital (Department of Psychiatry, Ansan Hospital)
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