Determinants of access to fertility preservation in women with breast cancer
- Authors
- Lee S.; Heytens E.; Moy F.; Ozkavukcu S.; Oktay K.
- Issue Date
- 2011
- Publisher
- Elsevier Inc.
- Keywords
- access; Breast cancer; chemotherapy; fertility preservation; referral
- Citation
- Fertility and Sterility, v.95, no.6, pp 1932 - 1936
- Pages
- 5
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- Fertility and Sterility
- Volume
- 95
- Number
- 6
- Start Page
- 1932
- End Page
- 1936
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/14144
- DOI
- 10.1016/j.fertnstert.2011.01.169
- ISSN
- 0015-0282
1556-5653
- Abstract
- Objective: To evaluate socioeconomic, demographic, and medical factors that influence the referral pattern - either before cancer treatment for fertility preservation (FP, early referral) or post-chemotherapy for assisted reproductive technology (PCART, delayed referral) - in women with breast cancer. Design: Secondary analysis. Setting: Academic medical centers. Patient(s): Three hundred fourteen patients with breast cancer who were counseled for FP (n = 218) or PCART (n = 96) from June 1999 to July 2009. Intervention(s): None. Main Outcome Measure(s): Factors favoring early referrals. Result(s): Mean age at diagnosis was higher in FP vs. PCART (35.3 ± 4.5 years vs. 33.9 ± 4.7 years). Ninety percent presented with cancer stage 1 or 2. From 2000 to 2009 the proportion of referrals for FP increased continually. In 2009, nearly all (95.5%) were for FP. The majority (63.8%) was referred from an academic center. Patients with a family history of breast cancer were more likely to consult for FP (75.2% vs. 64.3% without). There was no association with occupation, income, race, ethnicity, obstetric history, and prior infertility treatment. Only 22.9% of those counseled in PCART, compared with 45.0% in the FP group, proceeded with a procedure. Conclusion(s): There has been an increasing trend within the last 10 years for early referral of breast cancer patients to FP. Factors favoring early referrals are older age, early-stage cancer, family history of breast cancer, and academic center involvement. Those seen before cancer treatment are more likely to receive an intervention. © 2011 by American Society for Reproductive Medicine.
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Collections - 2. Clinical Science > Department of Obstetrics and Gynecology > 1. Journal Articles
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