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Cited 18 time in webofscience Cited 24 time in scopus
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Long-Term Outcomes of Prophylactic Endoscopic Histoacryl Injection for Gastric Varices with a High Risk of Bleeding

Authors
Chang, Yun JungPark, Jong-JaeJoo, Moon KyungLee, Beom JaeYun, Jae-WonYoon, Dae-WoongKim, Ji HoonYeon, Jong EunKim, Jae SeonByun, Kwan SooBak, Young-Tae
Issue Date
Aug-2010
Publisher
Kluwer Academic/Plenum Publishers
Keywords
Gastric varices; Endoscopic sclerotherapy; Butyl cyanoacrylate
Citation
Digestive Diseases and Sciences, v.55, no.8, pp 2391 - 2397
Pages
7
Indexed
SCI
SCIE
SCOPUS
Journal Title
Digestive Diseases and Sciences
Volume
55
Number
8
Start Page
2391
End Page
2397
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/14658
DOI
10.1007/s10620-009-1023-x
ISSN
0163-2116
1573-2568
Abstract
Purpose Endoscopic histoacryl injection (EHI) is reported to be an effective treatment modality for bleeding gastric varices (GVs) but controversial as a prophylactic treatment for non-bleeding GVs because efficacy and safety have yet to be determined. The aim of this study was to evaluate safety and long-term outcomes of prophylactic EHI for non-bleeding GVs with a high risk of bleeding. Methods Thirty-three patients (23 males/10 females, mean age 56.6 years old) with a high risk of gastric variceal bleeding (large tumorous (27), red color sign (14) or rapidly growing in size (1)) underwent EHI. According to the grade of GVs, 25 patients belonged to F3, seven to F2, and one to F1. In terms of the locations of GVs, four patients belonged to type IGV1, 21 to type GOV2, and eight to type GOV1. Results Obliteration of GVs was achieved in all of the treated patients. Twenty-three patients required one session and ten needed more than two sessions to obliterate their GVs. A mean volume of histoacryl used per session was 2.0 ml. Complications related to the procedure included immediate bleeding in two patients and bacteremia in one patient. The mean duration of follow-up was 12.2 months and eradication of GVs was achieved in 21 (95%) of 22 patients who were followed-up more than 3 months. Index GVs recurred in three of 21 patients (14%) and re-bleeding in index GVs after EHI occurred in two of 26 patients (8%). Conclusions Prophylactic EHI can be a promising procedure for eradication of non-bleeding GVs in case with a high risk of bleeding.
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Kim, Jae Seon
Guro Hospital (Department of Gastroenterology and Hepatology, Guro Hospital)
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