Antimicrobial Prophylaxis Using a 2nd Generation Cephalosporin after Laparoscopic Colorectal Resection: A Randomized Trial of 1-day vs. 3-day
- Authors
- Kwak, Han Deok; Choi, Dong Jin; Woo, Si Uk; Kim, Jin; Urn, Jun Won; Kim, Seon Hahn
- Issue Date
- Jun-2010
- Publisher
- KOREAN SURGICAL SOCIETY
- Keywords
- Antimicrobial prophylaxis; Monotherapy; Laparoscopic colorectal surgery; Surgical site infection; Hospital acquired infection
- Citation
- JOURNAL OF THE KOREAN SURGICAL SOCIETY, v.78, no.6, pp 385 - 389
- Pages
- 5
- Indexed
- SCOPUS
KCI
- Journal Title
- JOURNAL OF THE KOREAN SURGICAL SOCIETY
- Volume
- 78
- Number
- 6
- Start Page
- 385
- End Page
- 389
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/14810
- DOI
- 10.4174/jkss.2010.78.6.385
- ISSN
- 2233-7903
2093-0488
- Abstract
- Purpose: We performed this study to compare 1-day group using a 2nd generation cephalsporin with 3-day group for evaluating hospital acquired infection. Methods: The patients undenvent laparoscopic colorectal surgery at Korea University Medical Center Anam Hospital, from August, 2007 to June, 2008. They were randomly allocated to 2 groups: 1-day or 3-day group. A 2nd generation cephalosporin was administered within 1 hour before surgery with 12-hour intervals. In cases of suspected infection, further studies were done to identify infection. Results: The study included 154 patients (1-day group - 78, vs. 3-day group - 76). No differences were noted between the 2 groups in age, body mass index, smoking, diabetes mellitus, corticosteroid-use were noted. Gender (P=0.011) and mean operative time (P=0.047) between the 2 groups were different. The preventive rates of infection were 87.18% in the 1-day group compared with 82.89% in the 3-day group (P=0.456). Conclusion: Our prospective randomized control study concluded that there were no differences between the 1-day and 3-day group in hospital acquired infection. We could come to the conclusion that 1-day antimicrobial agent in laparoscopic colorectal surgery would be adequate in preventing infection. (J Korean Surg Soc 2010;78:385-389)
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- Appears in
Collections - 2. Clinical Science > Department of Colon and Rectal Surgery > 1. Journal Articles
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