Advanced Gastric Cancer in the Middle One-third of the Stomach: Should Surgenos Perform Total Gastrectomy?
- Authors
- Jang, You-Jin; Park, Man-Sik; Kim, Jong-Han; Park, Sung-Soo; Park, Seung-Heum; Kim, Seung-Joo; Kim, Chong-Suk; Mok, Young-Jae
- Issue Date
- 1-May-2010
- Publisher
- WILEY
- Keywords
- middle-third AGC; extent of gastric resection; long-term prognosis; surgical option for mid-gastric cancer
- Citation
- JOURNAL OF SURGICAL ONCOLOGY, v.101, no.6, pp 451 - 456
- Pages
- 6
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- JOURNAL OF SURGICAL ONCOLOGY
- Volume
- 101
- Number
- 6
- Start Page
- 451
- End Page
- 456
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/14874
- DOI
- 10.1002/jso.21431
- ISSN
- 0022-4790
1096-9098
- Abstract
- Background and Objectives: To determine which optimal surgical procedure for middle-third advanced gastric cancer (AGC) based on comparative study of the long-term prognosis between total gastrectomy (TG) and distal gastrectomy (DG). Methods: Between March 1993 and December 2005, 402 patients with middle-third AGC who underwent gastric resection were enrolled in this study. We analyzed the long-term prognosis according to the length of the proximal resection margin (PRM) and the extent of gastric resection, and determined independent prognostic factors. Results: TG was performed in 244 patients (60.7%) and DG was performed in 158 patients (39.3%). There were no significant differences in the 5-year survival rates according to the length of PRM. The 5-year survival rates of patients who underwent DG were significantly higher than the rates of the patients who underwent TG in curative cases (67.8% vs. 58.4%, P = 0.037). Nevertheless, there was no significant difference in the stage-stratified survival rates according to the extent of gastric resection. Multivariate analysis revealed that surgical curability, extent of lymphadenectomy, and stage were independent prognostic factors. Conclusion: If curative resection can be performed, the long-term prognosis of patients with middle-third AGC was not affected by the length of PRM or the extent of gastric resection. J. Surg. Oncol. 2010;101:451-456. (C) 2009 Wiley-Liss, Inc.
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- Appears in
Collections - 2. Clinical Science > Department of Foregut Surgery > 1. Journal Articles
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