Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction
- Authors
- Park, Hyo Eun; Koo, Bon Kwon; Lee, Wonjae; Cho, Youngjin; Park, Jin Sik; Choi, Ji Yong; Jeong, Myung Ho; Kim, Jong Hyun; Chae, Shung Chull; Kim, Young Jo; Nam, Chang Wook; Lee, Jae Hwan; Choi, Dong Hoon; Hong, Taek Jong; Chae, Jei Keon; Rhew, Jae Young; Kim, Kee Sik; Kim, Hyo Soo; Oh, Byung Hee; Park, Young Bae; KAMIR Investigators
- Issue Date
- May-2010
- Publisher
- JAPANESE CIRCULATION SOC
- Keywords
- Acute myocardial infarction; Circadian variation; Periodic variation
- Citation
- CIRCULATION JOURNAL, v.74, no.5, pp 970 - 976
- Pages
- 7
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- CIRCULATION JOURNAL
- Volume
- 74
- Number
- 5
- Start Page
- 970
- End Page
- 976
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/14879
- DOI
- 10.1253/circj.CJ-09-0344
- ISSN
- 1346-9843
1347-4820
- Abstract
- Background: The characteristics of the periodic variation in acute myocardial infarction (AMI) and the subsequent effect on management and prognosis have not been fully investigated in a large number of Asian populations. Methods and Results: From a prospective, observational multicenter online registry, 4,573 patients diagnosed as AMI in Korea from January to December 2006 were included. The highest incidence of AMI was between 8 a.m. and noon. The number of cases was highest in the winter and lowest in the autumn (13.6 vs 11.4 patients per day, P<0.001). Patients with symptom onset during working hours had a shorter time to first medical contact (203±288 min) compared with out-of-hours onset (230±288 min, P=0.003). In patients who underwent primary angioplasty, out-of hours symptom onset was associated with a greater time delay in both the patient's and the medical facility's response (door-to-balloon time out-of hours vs working hours: 101±54 min vs 84±44 min, P<0.001). In patients with ST-segment elevation myocardial infarction, symptoms to first medical contact showed a significant relationship to in-hospital mortality (for every 10 min of symptoms to first medical contact, odds ratio 1.006, 95% confidence interval 1.001-1.012, P=0.018) Conclusions: Circadian and periodic variation in AMI exists in Korean patients, which resulted in different patient behavior, hospital management and outcomes. (Circ J 2010; 74: 970 - 976)
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Collections - 2. Clinical Science > Department of Cardiology > 1. Journal Articles
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