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Cited 41 time in webofscience Cited 38 time in scopus
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Chronic hepatitis B: whom to treat and for how long? Propositions, challenges, and future directionsopen access

Authors
Ahn, Sang HoonChan, Henry L. Y.Chen, Pei-JerCheng, JunGoenka, Mahesh K.Hou, JinlinLim, Seng GeeOmata, MasaoPiratvisuth, TeerhaXie, QingYim, Hyung JoonYuen, Man-Fung
Issue Date
Mar-2010
Publisher
SPRINGER
Keywords
Chronic hepatitis B (CHB); Hepatitis B virus (HBV); Nucleoside/nucleotide analog; Interferon alfa; HBV DNA; ALT
Citation
HEPATOLOGY INTERNATIONAL, v.4, no.1, pp.386 - 395
Indexed
SCIE
SCOPUS
Journal Title
HEPATOLOGY INTERNATIONAL
Volume
4
Number
1
Start Page
386
End Page
395
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/15122
DOI
10.1007/s12072-010-9163-9
ISSN
1936-0533
Abstract
Recent guidelines of the American Association for the Study of Liver Diseases, the European Association for the Study of the Liver, and the Asian Pacific Association for the Study of the Liver 2008 update of the "Asian-Pacific consensus statement on the management of chronic hepatitis B" offer comprehensive recommendations for the general management of chronic hepatitis B (CHB). These recommendations highlight preferred approaches to the prevention, diagnosis, and treatment of CHB. Nonetheless, the results of recent studies have led to an improved understanding of the disease and a belief that current recommendations on specific therapeutic considerations, including CHB treatment initiation and cessation criteria, particularly in patient populations with special circumstances, can be improved. Twelve experts from the Asia-Pacific region formed the Asia-Pacific Panel Recommendations for the Optimal Management of Chronic Hepatitis B (APPROACH) Working Group to review, challenge, and assess relevant new data and inform future updates of CHB treatment guidelines. The significance of and controversy about reported findings were discussed and debated in an expert meeting of the Working Group in Beijing, China, in November 2008. This review paper attempts to identify areas requiring improved CHB management and provide suggestions for future guideline updates, with special emphasis on treatment initiation and duration.
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Yim, Hyung Joon
Ansan Hospital (Department of Gastroenterology and Hepatology, Ansan Hospital)
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