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Cited 9 time in webofscience Cited 10 time in scopus
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Abdominal Obesity as a Risk Factor for the Development of Erosive Esophagitis in Subjects with a Normal Esophago-Gastric Junction

Authors
Koo, Ja SeolLee, Sang WooPark, Sun MinJung, Sung WooYim, Hyung JoonPark, Jong JaeChun, Hoon JaiLee, Hong SikChoi, Jai HyunKim, Chang DuckRyu, Ho Sang
Issue Date
Dec-2009
Publisher
EDITORIAL OFFICE GUT & LIVER
Keywords
Abdominal obesity; Erosive esophagitis; Causality
Citation
GUT AND LIVER, v.3, no.4, pp.276 - 284
Indexed
SCIE
SCOPUS
KCI
OTHER
Journal Title
GUT AND LIVER
Volume
3
Number
4
Start Page
276
End Page
284
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/15628
DOI
10.5009/gnl.2009.3.4.276
ISSN
1976-2283
Abstract
Background/Aims: Obesity is reported to be associated with erosive esophagitis (EE). However, the temporal association of obesity and abdominal obesity with EE is unclear. We conducted this study to investigate the temporal association of obesity, especially abdominal obesity with EE. Methods: Among 1,182 subjects who underwent health screening examinations including upper endoscopy in both 2003 and 2006, a total 1,029 subjects with a normal esophagogastric junction on upper endoscopy in 2003 were enrolled. All subjects completed questionnaires and anthropometric measurements were obtained twice by trained personnels. The patients with newly developed EE were compared to the subjects without newly developed EE. Results: Among 1,029 subjects, 42 (4.1%) were newly diagnosed with EE and 82 (8.0%) with hiatal hernia. The mean body mass index (BMI) in both examinations was significantly different between the two groups based on the development of erosive esophagitis (p<0.05 in both examinations). The mean waist circumference (WC) in both examinations was also significantly different between the two groups (p<0.01 in both examinations). The multivariate analysis demonstrated that EE was not associated with the BMI in 2003 and the increase of BMI; however, it was associated with the WC in 2003 (Odds ratio, 7.21; 95% CI, 1.78 to 29.19; >90 cm vs <80 cm). Conclusions: Our study showed that abdominal circumference is an independent risk factor for EE, demonstrating a temporal relationship between abdominal obesity and EE. (Gut and Liver 2009;3: 276-284)
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Lee, Sang Woo
안산병원 (Department of Gastroenterology and Hepatology, Ansan Hospital)
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