Scanning laser polarimetry and optical coherence tomography for detection of retinal nerve fiber layer defects.
- Authors
- Oh J.H.; Kim Y.Y.
- Issue Date
- 2009
- Keywords
- Optical coherence tomography; Red-free fundus photography; Retinal nerve fiber layer defects; Scanning laser polarimetry
- Citation
- Korean journal of ophthalmology : KJO, v.23, no.3, pp 169 - 175
- Pages
- 7
- Indexed
- SCOPUS
KCICANDI
- Journal Title
- Korean journal of ophthalmology : KJO
- Volume
- 23
- Number
- 3
- Start Page
- 169
- End Page
- 175
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/16536
- DOI
- 10.3341/kjo.2009.23.3.169
- ISSN
- 1011-8942
2092-9382
- Abstract
- PURPOSE: To compare the ability of scanning laser polarimetry with variable corneal compensation (GDx-VCC) and Stratus optical coherence tomography (OCT) to detect photographic retinal nerve fiber layer (RNFL) defects. METHODS: This retrospective cross-sectional study included 45 eyes of 45 consecutive glaucoma patients with RNFL defects in red-free fundus photographs. The superior and inferior temporal quadrants in each eye were included for data analysis separately. The location and presence of RNFL defects seen in red-free fundus photographs were compared with those seen in GDx-VCC deviation maps and OCT RNFL analysis maps for each quadrant. RESULTS: Of the 90 quadrants (45 eyes), 31 (34%) had no apparent RNFL defects, 29 (32%) had focal RNFL defects, and 30 (33%) had diffuse RNFL defects in red-free fundus photographs. The highest agreement between GDx-VCC and red-free photography was 73% when we defined GDx-VCC RNFL defects as a cluster of three or more color-coded squares (p<5%) along the traveling line of the retinal nerve fiber in the GDx-VCC deviation map (kappa value, 0.388; 95% confidence interval (CI), 0.195 to 0.582). The highest agreement between OCT and red-free photography was 85% (kappa value, 0.666; 95% CI, 0.506 to 0.825) when a value of 5% outside the normal limit for the OCT analysis map was used as a cut-off value for OCT RNFL defects. CONCLUSIONS: According to the kappa values, the agreement between GDx-VCC deviation maps and red-free photography was poor, whereas the agreement between OCT analysis maps and red-free photography was good.
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- Appears in
Collections - 2. Clinical Science > Department of Ophthalmology > 1. Journal Articles
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