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Cited 23 time in webofscience Cited 24 time in scopus
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Clinical features and treatment outcomes of upper gastrointestinal bleeding in patients with cirrhosis

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dc.contributor.authorSeo, Yeon Seok-
dc.contributor.authorKim, Youn Ho-
dc.contributor.authorAhn, Sang Hoon-
dc.contributor.authorYu, Sang Kyun-
dc.contributor.authorBaik, Soon Koo-
dc.contributor.authorChoi, Sung Kyu-
dc.contributor.authorHeo, Jeong-
dc.contributor.authorHahn, Taeho-
dc.contributor.authorYoo, Tae Woo-
dc.contributor.authorCho, Se Hyun-
dc.contributor.authorLee, Hyun Woong-
dc.contributor.authorKim, Ju Hyun-
dc.contributor.authorCho, Mong-
dc.contributor.authorPark, Sang Hoon-
dc.contributor.authorKim, Byung Ik-
dc.contributor.authorHan, Kwang Hyub-
dc.contributor.authorUm, Soon Ho-
dc.date.available2020-11-03T09:49:58Z-
dc.date.issued2008-08-
dc.identifier.issn1011-8934-
dc.identifier.issn1598-6357-
dc.identifier.urihttps://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/16860-
dc.description.abstractWith recent progress in treatment modalities, mortality from upper gastrointestinal (UGI) bleeding has decreased appreciably. The aim of this study was to establish how UGI bleeds are managed in Korean patients with cirrhosis and to evaluate treatment outcomes. A total of 479 episodes of acute UGI bleeding in 464 patients with cirrhosis were included during a six-month period at nine tertiary medical centers. Treatment outcomes were assessed by failure to control bleeding, rebleeding and mortality. The source of bleeding was esophagogastric varices in 77.7% of patients, nonvariceal lesions in 15.9%, and undefined in 6.5%. For control of bleeding, endoscopic and pharmacologic treatments were used in 74.7% and 81.9% of patients, respectively. Variceal ligation was a major technique for endoscopic treatment (90%), and terlipressin and somatostatin were the main pharmacologic agents used (96.4%). Initial hemostasis was achieved in 86.8% of cases, but rebleeding occurred in 3.8% and 16.8% of cases within five days and six weeks of hemorrhage, respectively. Five-day and six-week mortality were 11.3% and 25.9%, respectively. Survival of patients with variceal bleeding seems to be remarkably improved than previous reports, which may suggest the advances in hemostatic methods for control of variceal hemorrhage.-
dc.format.extent9-
dc.language영어-
dc.language.isoENG-
dc.publisherKOREAN ACAD MEDICAL SCIENCES-
dc.titleClinical features and treatment outcomes of upper gastrointestinal bleeding in patients with cirrhosis-
dc.typeArticle-
dc.publisher.location대한민국-
dc.identifier.doi10.3346/jkms.2008.23.4.635-
dc.identifier.scopusid2-s2.0-50449091054-
dc.identifier.wosid000258936600011-
dc.identifier.bibliographicCitationJOURNAL OF KOREAN MEDICAL SCIENCE, v.23, no.4, pp 635 - 643-
dc.citation.titleJOURNAL OF KOREAN MEDICAL SCIENCE-
dc.citation.volume23-
dc.citation.number4-
dc.citation.startPage635-
dc.citation.endPage643-
dc.type.docTypeArticle-
dc.identifier.kciidART001270895-
dc.description.isOpenAccessY-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.relation.journalResearchAreaGeneral & Internal Medicine-
dc.relation.journalWebOfScienceCategoryMedicine, General & Internal-
dc.subject.keywordPlusRECURRENT VARICEAL HEMORRHAGE-
dc.subject.keywordPlusPORTAL-HYPERTENSION-
dc.subject.keywordPlusESOPHAGEAL-VARICES-
dc.subject.keywordPlusCONSENSUS WORKSHOP-
dc.subject.keywordPlusIMPROVED SURVIVAL-
dc.subject.keywordPlusCONTROLLED TRIAL-
dc.subject.keywordPlusLIVER-CIRRHOSIS-
dc.subject.keywordPlusPREVENTION-
dc.subject.keywordPlusMETAANALYSIS-
dc.subject.keywordPlusPROPRANOLOL-
dc.subject.keywordAuthorliver cirrhosis-
dc.subject.keywordAuthorvaricose veins-
dc.subject.keywordAuthorHemorrhage-
dc.subject.keywordAuthorHemostasis-
dc.subject.keywordAuthorprevention and control-
dc.subject.keywordAuthorprognosis-
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Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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