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Carotid intima-media thickness in Parkinson's disease
- Authors
- Lee, Jong-Moon; Park, Kun-Woo; Seo, Woo-Keun; Park, Moon Ho; Han, Changsu; Jo, Inho; Jo, Sangmee Ahn
- Issue Date
- Dec-2007
- Publisher
- WILEY-LISS
- Keywords
- Parkinson's disease; intima-media thickness; atherosclerosis
- Citation
- MOVEMENT DISORDERS, v.22, no.16, pp 2446 - 2449
- Pages
- 4
- Indexed
- SCIE
SCOPUS
- Journal Title
- MOVEMENT DISORDERS
- Volume
- 22
- Number
- 16
- Start Page
- 2446
- End Page
- 2449
- ISSN
- 0885-3185
1531-8257
- Abstract
- There have been a few studies and inconsistent results regarding the coincidence of Parkinson's disease (PD) and atherosclerotic diseases, such as cerebrovascular disease. Carotid intima-media thickness (IMT) is a known marker for subclinical atherosclerosis. The aim of this study was to investigate the carotid IMT between PD patients and controls. We studied 43 patients with PD and 86 matched controls. The carotid IMT in PD patients was significantly smaller than in controls (0.796 +/- 0.179 mm vs. 0.913 +/- 0.237 mm, P < 0.05). In multivariate analysis, the carotid IMT was inversely associated with the duration of levodopa medication and the severity of PD. These results suggest that PD patients have a lower risk of atherosclerosis. (c) 2007 Movement Disorder Society.
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Related Researcher
- Han, Changsu
- Ansan Hospital (Department of Psychiatry, Ansan Hospital)