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Cited 5 time in webofscience Cited 7 time in scopus
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Prepregnancy Factors Are Associated with Development of Hypertension Later in Life in Women with Pre-Eclampsia

Authors
Cho, Geum JoonKim, Ho YeonPark, Jong HeonAhn, Ki-HoonHong, Soon-CheolKim, Hai-JoongHan, Sun WonOh, Min-Jeong
Issue Date
1-Jul-2019
Publisher
MARY ANN LIEBERT, INC
Keywords
prepregnancy; pre-eclampsia; hypertension
Citation
JOURNAL OF WOMENS HEALTH, v.28, no.7, pp.984 - 989
Indexed
SCIE
SSCI
SCOPUS
Journal Title
JOURNAL OF WOMENS HEALTH
Volume
28
Number
7
Start Page
984
End Page
989
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/1820
DOI
10.1089/jwh.2018.7165
ISSN
1540-9996
Abstract
Background: The aim of our study was to investigate the prepregnancy characteristics that are risk factors for the development of hypertension (HTN) and identify prepregnancy factors for the development of HTN in women affected by pre-eclampsia in their first pregnancy. Methods: We enrolled 1910 women who had undergone a National Health Screening Examination through the National Health Insurance Corporation between 2002 and 2003, and who had their first delivery affected by pre-eclampsia in 2004. Women were classified as having HTN if they were newly diagnosed with HTN from 2005 through 2012. Results: After 8 years of follow-up, 7.7% (148/1910) of pre-eclamptic women developed HTN. Using the Cox proportional hazards model, old age (hazard ratio [HR] 3.92, 95% confidence interval [CI] 2.47-6.23), a family history of HTN (HR 2.28, 95% CI 1.46-3.58), prepregnancy obesity (HR 3.74, 95% CI 2.50-5.59), and high blood pressure (BP) (HR 2.78, 95% CI 1.85-4.19) were independently associated with the development of HTN. Conclusions: The results show that the development of HTN in pre-eclamptic women is related to prepregnancy factors. Recognizing who subsequently develops HTN postpartum in pre-eclamptic women with these prepregnancy factors could lead to early identification and lifestyle interventions, which could reduce the burden of cardiovascular disease.
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Cho, Geum Joon
Guro Hospital (Department of Obstetrics and Gynecology, Guro Hospital)
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