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A case of primary small cell neuroendocrine carcinoma of the liver

Authors
Kim K.J.Yim H.J.Kim M.J.Choung R.S.Yeon J.E.Lee H.S.Byun K.S.Lee S.W.Choi J.H.Ryu H.S.Lee C.H.Hyun J.H.Lee E.S.Kim Y.S.
Issue Date
2006
Keywords
Liver; Small cell neuroendocrine carcinoma; Immunohistochemical stain
Citation
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, v.48, no.1, pp.37 - 41
Indexed
SCOPUS
KCI
Journal Title
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume
48
Number
1
Start Page
37
End Page
41
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/19252
ISSN
1598-9992
Abstract
Small cell neuroendocrine carcinoma is a type of undifferentiated, malignant neuroendocrine tumor. Most of neuroendocrine tumors exhibit well-differentiated features and are classified as carcinoid tumors. However, carcinomas of the liver with anaplastic characters, which are classified as small-cell carcinomas are extremely rare and only few cases have been reported in the literature. We report an unusual case of primary small cell neuroendocrine carcinoma of the liver in a 67-year-old man. The patient was found to have a palpable mass on right upper quadrant of abdomen on physical examination. The diagnosis was made by immunohistochemical stains of biopsied specimen from the liver. Other possible primary site was excluded by radiologic and endoscopic evaluations. The tumor was composed of small monotonous and hyperchromatic poorly differentiated cells with higher nuclear to cytoplasmic ratio, and were positive for neuroendocrine tissue markers such as synaptophysin, c-kit, and CD56.
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2. Clinical Science > Department of Pathology > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

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Yeon, Jong Eun
Guro Hospital (Department of Gastroenterology and Hepatology, Guro Hospital)
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