Clinical validation of scoring systems of postoperative pancreatic fistula after pancreatoduodenectomy: applicability to Eastern cohorts?
DC Field | Value | Language |
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dc.contributor.author | Kang, Jae Seung | - |
dc.contributor.author | Park, Taesung | - |
dc.contributor.author | Han, Youngmin | - |
dc.contributor.author | Lee, Seungyeon | - |
dc.contributor.author | Kim, Jae Ri | - |
dc.contributor.author | Kim, Hongbeom | - |
dc.contributor.author | Kwon, Wooil | - |
dc.contributor.author | Kim, Sun-Whe | - |
dc.contributor.author | Heo, Jin Seok | - |
dc.contributor.author | Choi, Seong Ho | - |
dc.contributor.author | Choi, Dong Wook | - |
dc.contributor.author | Kim, Song Cheol | - |
dc.contributor.author | Hong, Tae Ho | - |
dc.contributor.author | Yoon, Dong Sup | - |
dc.contributor.author | Park, Joon Seong | - |
dc.contributor.author | Park, Sang Jae | - |
dc.contributor.author | Han, Sung-Sik | - |
dc.contributor.author | Choi, Sae-Byeol | - |
dc.contributor.author | Ki, Joo Seop | - |
dc.contributor.author | Lim, Chang-Sup | - |
dc.contributor.author | Jang, Jin-Young | - |
dc.date.available | 2020-11-02T06:35:38Z | - |
dc.date.issued | 2019-06 | - |
dc.identifier.issn | 2304-3881 | - |
dc.identifier.issn | 2304-389X | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/1963 | - |
dc.description.abstract | Background: Although several prediction models for the occurrence of postoperative pancreatic fistula (POPF) after pancreatoduodenectomy (PD) exist, all were established using Western cohorts. Large-scale external validation studies in Eastern cohorts that consider demographic variables including lower body mass index (BMI) are scarce. The purpose of this study was to externally validate POPF prediction models using nationwide large-scale Korean cohorts. Methods: Nine tertiary university hospitals in the Republic of Korea participated. Patients' preoperative characteristics, intraoperative factors, and pathologic findings were evaluated. POPF grades were determined according to the 2016 International Study Group on Pancreatic Surgery definition. Three POPF risk models (Callery, Roberts, and Mungroop) were selected for external validation. Results: A total of 1,898 PD patients were enrolled. A non-pancreatic disease diagnosis [hazard ratio (HR), 1.856; 95% confidence interval (CI), 1.223-2.817; P=0.004), higher preoperative BMI (HR, 1.069; 95% CI, 1.019-1.121; P=0.006), and soft pancreatic texture (HR, 1.859; 95% CI, 1.264-2.735; P=0.002) were independent risk factors for clinically relevant POPF (CR-POPF). The area under the receiver operating characteristic curve (AUC) values were 0.61, 0.64, and 0.63 on the Callery, Roberts, and Mungroop models, respectively; all were lower than those published in each external validation study. Conclusions: Western POPF prediction models performed less well when applied to Korean cohorts. Thus, a large-scale Eastern-specific and externally validated POPF prediction model is needed. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | AME PUBL CO | - |
dc.title | Clinical validation of scoring systems of postoperative pancreatic fistula after pancreatoduodenectomy: applicability to Eastern cohorts? | - |
dc.type | Article | - |
dc.publisher.location | 캐나다 | - |
dc.identifier.doi | 10.21037/hbsn.2019.03.17 | - |
dc.identifier.wosid | 000470015000002 | - |
dc.identifier.bibliographicCitation | HEPATOBILIARY SURGERY AND NUTRITION, v.8, no.3, pp 211 - 218 | - |
dc.citation.title | HEPATOBILIARY SURGERY AND NUTRITION | - |
dc.citation.volume | 8 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 211 | - |
dc.citation.endPage | 218 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | MULTIINSTITUTIONAL EXTERNAL VALIDATION | - |
dc.subject.keywordPlus | RISK SCORE | - |
dc.subject.keywordPlus | TRIAL | - |
dc.subject.keywordAuthor | Pancreatic fistula | - |
dc.subject.keywordAuthor | pancreatoduodenectomy (PD) | - |
dc.subject.keywordAuthor | predictive score | - |
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