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Clinical features of chronic pancreatitis in Korea: A multicenter nationwide study

Authors
Ji K.R.Jun K.L.Kim Y.-T.Dong K.L.Dong W.S.Kyu T.L.Ho G.K.Jae S.K.Hong S.L.Tae N.K.Myung H.R.Jong H.M.Lee J.Choi H.-S.Woo J.L.Byung M.Y.Yong B.Y.
Issue Date
2005
Keywords
Chronic pancreatitis; Chronic pancreatitis, etiology; Chronic pancreatitis, korean multicenter study; Pancreatic cancer
Citation
Digestion, v.72, no.4, pp.207 - 211
Indexed
SCOPUS
Journal Title
Digestion
Volume
72
Number
4
Start Page
207
End Page
211
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/20140
DOI
10.1159/000089414
ISSN
0012-2823
Abstract
Background/Aims: No reliable nationwide clinical data about chronic pancreatitis (CP) was available in Korea. The etiology and clinical features of CP were investigated using a multicenter nationwide study. Methods: 814 cases of CP were enrolled retrospectively over the past 4 years at 13 hospitals. The following data were obtained from all patients: etiology, symptoms, complications, and surgery. Result: Alcohol (64.3%) was the major cause of CP and idiopathic CP (20.8%) was the second most common form. Mean patient age was 50.6 years and the male:female ratio was 6:1 (24:1 for alcoholic CP vs. 2:1 in idiopathic CP, p < 0.001). Diabetes (31.6%), pseudocysts (28.4%), biliary stricture (13.9%), and pancreatic ascites (6.6%) were the main complications. Of these, diabetes (35 vs. 26%) and pseudocyst (33.7 vs. 21.9%) were more frequent in alcoholic than in idiopathic CP. Pancreatic cancer developed in 25 patients (3.1%) during follow-up and their mean age was 59.1 years. Conclusions: In Korea, alcohol is the most common etiology of CP. Moreover, diabetes and pseudocysts are frequent complications, especially in alcoholic CP, and pancreatic cancer development is not infrequent. Copyright © 2005 S. Karger AG.
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안암병원 (Department of Gastroenterology and Hepatology, Anam Hospital)
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