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Cited 7 time in webofscience Cited 8 time in scopus
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Validation of the Korean Stroop Test in Diagnosis of Minimal Hepatic Encephalopathyopen access

Authors
Yoon, Eileen L.Jun, Dae WonJeong, Jae YoonKim, Tae YeobSong, Do SeonAhn, Sang BongKim, Hee YeonJung, Young KulSong, Myeong JunKim, Sung EunKim, Hyoung SuJeong, Soung WonKim, Sang GyuneLee, Tae HeeCho, Yong KyunKim, Jae-KwanRyu, Hokyoung
Issue Date
29-May-2019
Publisher
NATURE PUBLISHING GROUP
Citation
SCIENTIFIC REPORTS, v.9
Indexed
SCIE
SCOPUS
Journal Title
SCIENTIFIC REPORTS
Volume
9
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/2016
DOI
10.1038/s41598-019-44503-w
ISSN
2045-2322
Abstract
The burden of minimal hepatic encephalopathy (MHE) is significant, but no universal criteria for diagnosis have been established. We aimed to validate the Korean Stroop Test for MHE screening. Chronic hepatitis B-related liver cirrhosis patients were recruited prospectively from 13 centers. The Korean Stroop Test consisted of two Stroop-off states (color and word) and two Stroop-on states (inhibition and switching). Accuracy adjusted psychomotor speed (rate correct score) of these tests were analyzed. Sex- and age- adjusted rate correct scores of these tests were rated as the Korean Stroop Score (K-Stroop score). MHE was diagnosed when Portosystemic Encephalopathy Syndrome Test (PHES) scores were below -4. A total of 220 liver cirrhosis patients and 376 healthy controls were enrolled. Prevalence of MHE was 20.6% in cirrhosis patients. Rate correct scores and the K-Stroop score showed significant differences between healthy controls, cirrhosis patients without MHE, and cirrhosis patients with MHE. The rate correct score of the K-Stroop score was 0.74 (95% Confidence Interval: 0.66-0.83, P < 0.001). Female gender and the K-Stroop score were significant for MHE diagnosis. The Korean Stroop Test is simple and valid for screening of MHE.
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Jung, Young Kul
Ansan Hospital (Department of Gastroenterology and Hepatology, Ansan Hospital)
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