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Cited 17 time in webofscience Cited 17 time in scopus
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G-protein beta(3) subunit C825T polymorphism tends to be associated with seasonal variation in young male college students

Authors
Lee, HJSung, SMHan, CSKim, YKKim, SHLee, MSJoe, SHJung, IKKim, L
Issue Date
2005
Publisher
KARGER
Keywords
seasonality; G-protein; polymorphism; heterosis
Citation
NEUROPSYCHOBIOLOGY, v.52, no.3, pp.135 - 139
Indexed
SCIE
SCOPUS
Journal Title
NEUROPSYCHOBIOLOGY
Volume
52
Number
3
Start Page
135
End Page
139
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/20174
DOI
10.1159/000087559
ISSN
0302-282X
Abstract
This study investigated the relationship between G-protein beta 3 subunit (GNB3) C825T polymorphism and seasonal variation in 189 young male college students. The subjects were genotyped for C825T and were evaluated by the Seasonality Pattern Assessment Questionnaire. The Global Seasonality Score (GSS) between the three genotypes revealed a marginal difference. The heterozygotes showed significantly higher seasonal variations in GSS than the homozygotes. The prevalence of heterozygotes tended to be higher in seasonals compared with normal subjects, although it was not statistically significant. These results suggest that GNB3 C825T polymorphism tends to be related to seasonal variation in mood and behavior in the normal population. Copyright (C) 2005 S. Karger AG, Basel.
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Lee, Heon Jeong
Anam Hospital (Department of Psychiatry, Anam Hospital)
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