만성 C형 간염의 치료Treatment of Chronic Hepatitis C
- Other Titles
- Treatment of Chronic Hepatitis C
- Authors
- 장윤정; 변관수
- Issue Date
- Dec-2004
- Publisher
- 대한소화기학회
- Keywords
- Chronic hepatitis C; Treatment; Pegylated interferon; Ribavirin
- Citation
- The Korean Journal of Gastroenterology, v.44, no.6, pp 301 - 307
- Pages
- 7
- Indexed
- SCOPUS
KCI
- Journal Title
- The Korean Journal of Gastroenterology
- Volume
- 44
- Number
- 6
- Start Page
- 301
- End Page
- 307
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/20214
- ISSN
- 1598-9992
2233-6869
- Abstract
- [한국어 초록 없음]
Chronic infection with HCV represents second most common cause of end-stage liver diseases and hepatocellular carcinoma in Korea. The introduction of new agents and regimens for the treatment of chronic hepatitis C, such as pegylated forms of interferon- (Peg-IFN) and combination with oral ribavirin has resulted in substantial improvement in sustained virologic response (SVR) rates. SVR rate of Peg-IFN and ribavirin combination therapy can be 40-46% of individuals infected with genotype 1 and approximately 75-85% with genotype 2 and 3. Peg-IFN/ribavirin combination therapy represents current standard therapy of chronic hepatitis C. This article reviews the treatment objectives, outcomes, optimal regimens, efficacy and predictors of response, monitoring during treatment, adverse events, retreatment of persons who failed to respond to previous treatments, and treatment of special patient groups in chronic hepatitis C.
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Collections - 2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles
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