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척수주위종괴로 단독 재발한 급성림프구성백혈병 1례Isolated Extramedullary Relapse of Acute Lymphoblastic Leukemia Presenting as an Paraspinal Mass

Other Titles
Isolated Extramedullary Relapse of Acute Lymphoblastic Leukemia Presenting as an Paraspinal Mass
Authors
김지영김희라우찬욱이정화정운용이광철
Issue Date
Apr-2004
Publisher
대한소아혈액종양학회
Keywords
Acute lymphoblastic leukemia; Extramedullary relapse; Paraspinal mass
Citation
Clinical Pediatric Hematology-Oncology, v.11, no.1, pp 68 - 73
Pages
6
Journal Title
Clinical Pediatric Hematology-Oncology
Volume
11
Number
1
Start Page
68
End Page
73
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/20549
ISSN
2233-5250
2233-4580
Abstract
Despite improvements in therapy, cases in which relapse occurs are still common in children with acute lymphoblastic leukemia (ALL). Most relapses occur in the bone marrow, and extramedullary relapse is most commonly in the central nerve system. Soft tissue mass lesion or spinal cord involvement is extremely unusual in ALL relapse. We experienced a 13-year-old boy who presented with extremity weakness and pain. He was diagnosed with ALL 4 years ago and achieved complete remission after systemic chemotherapy. Imaging study revealed a paraspinal mass which was invading the S1-2 vertebral body. Histopathologic examination revealed infiltrates composed of immature lymphoblasts with morphology identical with that of initially diagnosed bone marrow aspiration. Studies on bone marrow were negative for disease at this time. He was treated with irradiation and intrathecal chemotherapy, in addition to systemic chemotherapy. The mass has nearly disappeared, and he is planned for allogeneic bone marrow transplantation.
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2. Clinical Science > Department of Pathology > 1. Journal Articles
2. Clinical Science > Department of Pediatrics > 1. Journal Articles

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