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A case of primary pulmonary plasmacytoma presenting as endobronchial mass

Authors
Suh S.Y.Ko G.J.Kim C.H.Kim Y.H.Lee S.Y.Lee S.Y.Kim J.H.Shin C.Shim J.J.In K.H.Kang K.H.Yoo S.H.
Issue Date
2004
Publisher
Korean National Tuberculosis Association
Keywords
Endobronchial mass; Extramedullary plasmacytoma; Pulmonary plasmacytoma
Citation
Tuberculosis and Respiratory Diseases, v.56, no.6, pp 664 - 669
Pages
6
Indexed
SCOPUS
Journal Title
Tuberculosis and Respiratory Diseases
Volume
56
Number
6
Start Page
664
End Page
669
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/20783
DOI
10.4046/trd.2004.56.6.664
ISSN
0378-0066
Abstract
Extramedullary plasmacytoma(EMP) comprises 5% of all plasma cell neoplasms and commonly occurs in the upper airway or digestive tract. However, it rarely develops in the lungs. We present a case of primary pulmonary plasmacyotma in a 45 year old man, who presented as an endobronchial mass with a pleural effusion, but without evidence of multiple myeloma. The treatment options for EMP include surgery, surgery and radiotherapy, surgery and chemotherapy or chemotherapy alone. Surgery and radiation therapy appeared to be equally effective forms of treatment. The local recurrence rate was reported to be 30%, with 48% progressing to multiple myeloma, and median survival was reported to be 63-101 months. Our patient was initially treated with melphalan and prednisolone. However the disease progressed, and radiotherapy was combined with chemotherapy. In addition, the chemotherapy regimen was also changed to thalidomide and dexamethasone. The patient did not respond to this treatment regimen and finally died.
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Anam Hospital (Department of Pulmonary, Allergy, and Critical Care Medicine, Anam Hospital)
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