Detailed Information

Cited 11 time in webofscience Cited 13 time in scopus
Metadata Downloads

Medication Adherence Using Electronic Monitoring in Severe Psychiatric Illness: 4 and 24 Weeks after Discharge

Authors
Lee, YujinLee, Moon-SooJeong, Hyun-GhangYoun, Hyun-ChulKim, Seung-hyun
Issue Date
May-2019
Publisher
KOREAN COLL NEUROPSYCHOPHARMACOLOGY
Keywords
Adherence; Schizophrenia; Bipolar disorder; Medication Event Monitoring System; Drug monitoring
Citation
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE, v.17, no.2, pp.288 - 296
Indexed
SCIE
SCOPUS
KCI
Journal Title
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
Volume
17
Number
2
Start Page
288
End Page
296
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/2080
DOI
10.9758/cpn.2019.17.2.288
ISSN
1738-1088
Abstract
Objective: The purpose of this study was to examine post-hospitalization outpatient drug adherence in patients with severe psychiatric illness, including bipolar disorder and schizophrenia, and to investigate factors associated with drug adherence. Methods: Eighty-one patients diagnosed with schizophrenia or bipolar disorder who were hospitalized due to aggravation of psychiatric symptoms were monitored. At hospitalization, we conducted clinical assessments such as the Clinical Global Impression-Severity, Drug Attitude Inventory, Contour Drawing Rating Scale, Multidimensional Scale of Perceived Social Support scale, and patients' demographic factors. We measured drug adherence using the Medication Event Monitoring System (MEMS), pill count, and patients' self-report upon out-patients visits, 4 and 24 weeks after discharge. Results: The mean values of the various measures of adherence were as follows: MEMS (4 weeks) 84.8%, pill count (4 weeks) 94.6%, self-report (4 weeks) 92.6%, MEMS (24 weeks) 81.6%, pill count (24 weeks) 90.6%, and self-report (24 weeks) 93.6%. The adherence agreement between MEMS, pill count, and self-report was moderate (4 weeks intra-class correlation [ICC]= 0.54, 24 weeks ICC= 0.52). Non-adherence (MEMS <= 0.08) was observed in 26.4% of the patients at 4 weeks and 37.7% at 24 weeks. There was a negative correlation between drug adherence assessed 4 weeks after discharge and Contour Drawing Rating Scale difference score (r=-0.282, p< 0.05). A positive correlation was found between drug adherence assessed 24 weeks after discharge and Drug Attitude Inventory (r= 0.383, p< 0.01). Conclusion: Patients' attitude towards their medication and their degree of physical dissatisfaction influenced post-hospitalization drug adherence in severe psychiatric patients.
Files in This Item
There are no files associated with this item.
Appears in
Collections
2. Clinical Science > Department of Psychiatry > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Jeong, Hyun Ghang photo

Jeong, Hyun Ghang
Guro Hospital (Department of Psychiatry, Guro Hospital)
Read more

Altmetrics

Total Views & Downloads

BROWSE