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Cited 33 time in webofscience Cited 35 time in scopus
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The prognosis of liver cirrhosis in recent years in Korea

Authors
Kim, YSUm, SHLee, JWPark, DKKim, YSJin, YTChun, HJLee, HSLee, SWChoi, JHKim, CDHyun, IH
Issue Date
Dec-2003
Publisher
KOREAN ACAD MEDICAL SCIENCES
Keywords
liver cirrhosis; liver cirrhosis; alcoholic; prognosis; survival rate; survival analysis; carcinoma; hepatocellular; esophageal and gastric varices; hemorrhage
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.18, no.6, pp 833 - 841
Pages
9
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
Volume
18
Number
6
Start Page
833
End Page
841
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/20953
DOI
10.3346/jkms.2003.18.6.833
ISSN
1011-8934
1598-6357
Abstract
The survival of a recent series of 823 cirrhosis. patients who were followed up for a mean of 48 months was analyzed. Cirrhosis was ascribed to alcohol (26%), hepatitis Virus B (58%), hepatitis virus C (11%) or both (2%) or was cryptogenic (3%). Features of decompensation were observed in 51% of the patients at entry, and newly developed in 44% of compensated patients within 5 yr. The 5-yr survival after decompensation was 25%. The leading causes of death,were liver failure (53%), hepatocellular carcinoma (HCC, 23%), and variceal bleeding (10%). Early detection of HCC significantly improved the survival of cirrhosis patients. Biannual ultrasonography increased the detection rate of small HCC. Mortality of variceal hemorrhage was much lower in patients with Child-Pugh scores from 5 to 8 than in those with scores above 8 (5% vs. 52%). Endoscopic prophylaxis significantly decreased the incidence of first variceal hemorrhage, but the effect was insufficient to improve the rate of survival. Mortality of first spontaneous bacterial peritonitis was 18%. These data suggest that the mortality of major complications of liver cirrhosis has considerably decreased during the last two decades, while there was no remarkable improvement in long-term survival. More efficient management of etiologic factors would be required.
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5. Others > Others(Medicine) > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

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Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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