The first human case of hepatic dirofilariasis
- Authors
- Kim, Min Kyung; Kim, Chul Hwan; Yeom, Bom Woo; Park, Seong Hwan; Choi, Sang Yong; Choi, Jong Sang
- Issue Date
- Oct-2002
- Publisher
- KOREAN ACAD MEDICAL SCIENCES
- Keywords
- dirofilaria immitis; Nematoda; liver; human
- Citation
- JOURNAL OF KOREAN MEDICAL SCIENCE, v.17, no.5, pp 686 - 690
- Pages
- 5
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- JOURNAL OF KOREAN MEDICAL SCIENCE
- Volume
- 17
- Number
- 5
- Start Page
- 686
- End Page
- 690
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/21709
- DOI
- 10.3346/jkms.2002.17.5.686
- ISSN
- 1011-8934
1598-6357
- Abstract
- Most of human dirofilariasis are pulmonary or subcutaneous infections, but there have been a few reports of human dirofilariasis in unusual sites, such as large vessels, mesentery, peritoneal cavity, and spermatic cord. We present the first case of human hepatic dirofilariasis, which was surgically diagnosed. A 39-yr-old man without any evidence of systemic symptom was found incidentally to have a hepatic nodule during routine physical check-up. The histologic findings of the resected lesion showed a granulomatous lesion with central necrosis containing up to 35 transverse sections of a nematode, ranging 30-80 mum in diameter. Thin (1.5-5 mum) cuticle with transverse striations surrounded polymyarian and muscle bundles occupied a sixth of both sides of outer body cavity. Central portion of the body cavity was occupied with an intestine-like tubular structure and a larger reproductive tube. These microscopic findings were consistent with degenerated Dirofilaria immitis. Antibody test by enzyme-linked immunosorbent assay for patient serum reacted positively against adult D. immitis antigen.
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- Appears in
Collections - 2. Clinical Science > Department of Hepato-Biliary-Pancreatic Surgery > 1. Journal Articles
- 1. Basic Science > Department of Pathology > 1. Journal Articles
- 2. Clinical Science > Department of Pathology > 1. Journal Articles
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