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Cited 20 time in webofscience Cited 28 time in scopus
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The first human case of hepatic dirofilariasis

Authors
Kim, Min KyungKim, Chul HwanYeom, Bom WooPark, Seong HwanChoi, Sang YongChoi, Jong Sang
Issue Date
Oct-2002
Publisher
KOREAN ACAD MEDICAL SCIENCES
Keywords
dirofilaria immitis; Nematoda; liver; human
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.17, no.5, pp 686 - 690
Pages
5
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
Volume
17
Number
5
Start Page
686
End Page
690
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/21709
DOI
10.3346/jkms.2002.17.5.686
ISSN
1011-8934
1598-6357
Abstract
Most of human dirofilariasis are pulmonary or subcutaneous infections, but there have been a few reports of human dirofilariasis in unusual sites, such as large vessels, mesentery, peritoneal cavity, and spermatic cord. We present the first case of human hepatic dirofilariasis, which was surgically diagnosed. A 39-yr-old man without any evidence of systemic symptom was found incidentally to have a hepatic nodule during routine physical check-up. The histologic findings of the resected lesion showed a granulomatous lesion with central necrosis containing up to 35 transverse sections of a nematode, ranging 30-80 mum in diameter. Thin (1.5-5 mum) cuticle with transverse striations surrounded polymyarian and muscle bundles occupied a sixth of both sides of outer body cavity. Central portion of the body cavity was occupied with an intestine-like tubular structure and a larger reproductive tube. These microscopic findings were consistent with degenerated Dirofilaria immitis. Antibody test by enzyme-linked immunosorbent assay for patient serum reacted positively against adult D. immitis antigen.
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2. Clinical Science > Department of Hepato-Biliary-Pancreatic Surgery > 1. Journal Articles
1. Basic Science > Department of Pathology > 1. Journal Articles
2. Clinical Science > Department of Pathology > 1. Journal Articles

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