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Comparison of the Usefulness of the PHQ-8 and PHQ-9 for Screening for Major Depressive Disorder: Analysis of Psychiatric Outpatient Data

Authors
Shin, CheolminLee, Seung-HoonHan, Kyu-ManYoon, Ho-KyoungHan, Changsu
Issue Date
Apr-2019
Publisher
KOREAN NEUROPSYCHIATRIC ASSOC
Keywords
Depression; Major depressive disorder; PHQ-8; PHQ-9
Citation
PSYCHIATRY INVESTIGATION, v.16, no.4, pp.300 - 305
Indexed
SCIE
SSCI
SCOPUS
KCI
Journal Title
PSYCHIATRY INVESTIGATION
Volume
16
Number
4
Start Page
300
End Page
305
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/2231
DOI
10.30773/pi.2019.02.01
ISSN
1738-3684
Abstract
Objective This study aimed to demonstrate that the Patient Health Questionnaire (PHQ)-8 is not less useful than the PHQ-9 as a screening test for major depressive disorder (MDD). Methods We performed a retrospective analysis of 567 patients in psychiatric outpatient units. The Mini International Neuropsychiatric Interview was used to diagnose MDD. We derived the validity and reliability of the PHQ-8 and PHQ-9. To evaluate the ability of the PHQ-8 and PHQ-9 to discriminate MDD, we drew receiver operating characteristic (ROC) curves and compared the areas under the curves (AUCs). Results Of the 567 participants, 207 (36.5%) were diagnosed with MDD. Cronbach's as for the PHQ-8 and PHQ-9 were 0.892 and 0.876, respectively. Similar to the PHQ-9, the PHQ-8 was also associated with scores on the Hamilton Depression Rating Scale in a correlation analysis. When we drew ROC curves for the PHQ-8 and PHQ-9, there was no statistically significant difference in the AUCs. With a cutoff score of 10, the PHQ-8 showed a sensitivity of 58.3%, specificity of 83.1%, positive predictive value of 53.4%, and negative predictive value of 85.7%. Conclusion In a psychiatric outpatient sample, the PHQ-8 was as useful as the PHQ-9 for MDD screening.
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Ansan Hospital (Department of Psychiatry, Ansan Hospital)
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