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Validity of the specialized columnar epithelium as a diagnostic criterion of the short segment Barrett's esophagus.

Authors
Bak, Young-TaeJung, Gil ManYeon, Jong EunKim, Jae SeonByun, Kwan SooKim, Jin HoKim, Jong GukLee, Chang HongKim, Han KyeomWon, Nam Hee
Issue Date
Jul-1998
Publisher
대한내과학회
Keywords
Barrett' s esophagus; columnar-lined esophagus; gastroesophagela junction; goblet cell; interstinal metaplasia; specialized columar epithelium
Citation
The Korean Journal of Internal Medicine, v.13, no.2, pp.99 - 103
Indexed
SCOPUS
Journal Title
The Korean Journal of Internal Medicine
Volume
13
Number
2
Start Page
99
End Page
103
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/24965
DOI
10.3904/kjim.1998.13.2.99
ISSN
1226-3303
Abstract
Objective In areas where intestinal metaplasia of the stomach is highly prevalent, diagnosing Barrett’s esophagus solely by the presence of specialized columnar epithelium in the distal esophagus may lead to many false positive diagnoses. The aim of this study was to test the validity of the specialized columnar epithelium as a diagnostic criterion of the short segment Barrett’s esophagus in Korea. Methods During routine gastroscopy, the length of columnar-lined esophagus was measured and biopsy samples were taken from the mucosa immediately distal to the squamocolumnar junction. Under light microscopy, alcian blue-positive cells were identified. Results Prevalence of the specialized columnar epithelium in cases without the columnar-lined esophagus and with the short segment columnar-lined esophagus was 57.1% and 31.2%, respectively (P=0.0281). The specialized columnar epithelium is frequently seen around the cardia in Koreans with or without the columnar-lined esophagus. Conclusions Simple presence of the specialized columnar epithelium is not a valid criterion for a diagnosis of Barrett’s esophagus. We propose that both the short segment Barrett’s esophagus and the goblet cell metaplasia of the cardia might be grouped together under a title of “the specialized columnar epithelium around the gastroesophageal junction” as a potential preceding condition of adenocarcinoma around the cardia.
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1. Basic Science > Department of Pathology > 1. Journal Articles
2. Clinical Science > Department of Pathology > 1. Journal Articles
2. Clinical Science > Department of Internal Medicine > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

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