Detailed Information

Cited 0 time in webofscience Cited 7 time in scopus
Metadata Downloads

Characteristics and clinical outcomes of critically ill cancer patients admitted to Korean intensive care unitsopen access

Authors
Na S.J.Ha T.S.Koh Y.Suh G.Y.Koh S.O.Lim C.-M.Choi W.-I.Lee Y.-J.Kim S.C.Chon G.R.Kim J.H.Kim J.Y.Lim J.Park S.Kim H.C.Lee J.H.Lee J.H.Park J.Cho J.Jeon K.Validation of Simplified Acute Physiology Score 3 in Korean Intensive care unit (VSKI) study groupand the Korean Study Group On Respiratory Failure (KOSREF)
Issue Date
2018
Publisher
Korean Society of Critical Care Medicine
Keywords
Cancer; Critical care; Epidemiology; Hematologic neoplasm; Mortality
Citation
Acute and Critical Care, v.33, no.3, pp 121 - 129
Pages
9
Indexed
SCOPUS
KCI
Journal Title
Acute and Critical Care
Volume
33
Number
3
Start Page
121
End Page
129
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/29240
DOI
10.4266/acc.2018.00143
ISSN
2586-6052
2586-6060
Abstract
Background: The objective of this study was to investigate the characteristics and clinical outcomes of critically ill cancer patients admitted to intensive care units (ICUs) in Korea. Methods: This was a retrospective cohort study that analyzed prospective collected data from the Validation of Simplified Acute Physiology Score 3 (SAPS3) in Korean ICU (VSKI) study, which is a nationwide, multicenter, and prospective study that considered 5,063 patients from 22 ICUs in Korea over a period of 7 months. Among them, patients older than 18 years of age who were diagnosed with solid or hematologic malignancies prior to admission to the ICU were included in the present study. Results: During the study period, a total of 1,762 cancer patients were admitted to the ICUs and 833 of them were deemed eligible for analysis. Six hundred fifty-eight (79%) had solid tumors and 175 (21%) had hematologic malignancies, respectively. Respiratory problems (30.1%) was the most common reason leading to ICU admission. Patients with hematologic malignancies had higher Sequential Organ Failure Assessment (12 vs. 8, P < 0.001) and SAPS3 (71 vs. 69, P < 0.001) values and were more likely to be associated with chemotherapy, steroid therapy, and immunocompromised status versus patients with solid tumors. The use of inotropes/vasopressors, mechanical ventilation, and/or continuous renal replacement therapy was more frequently required in hematologic malignancy patients. Mortality rates in the ICU (41.7% vs. 24.6%, P < 0.001) and hospital (53.1% vs. 38.6%, P = 0.002) were higher in hematologic malignancy patients than in solid tumor patients. Conclusions: Cancer patients accounted for one-third of all patients admitted to the studied ICUs in Korea. Clinical characteristics were different according to the type of malignancy. Patients with hematologic malignancies had a worse prognosis than did patients with solid tumor. Copyright © 2018 The Korean Society of Critical Care Medicine
Files in This Item
Appears in
Collections
2. Clinical Science > Department of Pulmonary, Allergy, and Critical Care Medicine > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Kim, Je Hyeong photo

Kim, Je Hyeong
Ansan Hospital (Department of Pulmonary, Allergy, and Critical Care Medicine, Ansan Hospital)
Read more

Altmetrics

Total Views & Downloads

BROWSE