Characteristics and clinical outcomes of critically ill cancer patients admitted to Korean intensive care unitsopen access
- Authors
- Na S.J.; Ha T.S.; Koh Y.; Suh G.Y.; Koh S.O.; Lim C.-M.; Choi W.-I.; Lee Y.-J.; Kim S.C.; Chon G.R.; Kim J.H.; Kim J.Y.; Lim J.; Park S.; Kim H.C.; Lee J.H.; Lee J.H.; Park J.; Cho J.; Jeon K.; Validation of Simplified Acute Physiology Score 3 in Korean Intensive care unit (VSKI) study group; and the Korean Study Group On Respiratory Failure (KOSREF)
- Issue Date
- 2018
- Publisher
- Korean Society of Critical Care Medicine
- Keywords
- Cancer; Critical care; Epidemiology; Hematologic neoplasm; Mortality
- Citation
- Acute and Critical Care, v.33, no.3, pp 121 - 129
- Pages
- 9
- Indexed
- SCOPUS
KCI
- Journal Title
- Acute and Critical Care
- Volume
- 33
- Number
- 3
- Start Page
- 121
- End Page
- 129
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/29240
- DOI
- 10.4266/acc.2018.00143
- ISSN
- 2586-6052
2586-6060
- Abstract
- Background: The objective of this study was to investigate the characteristics and clinical outcomes of critically ill cancer patients admitted to intensive care units (ICUs) in Korea. Methods: This was a retrospective cohort study that analyzed prospective collected data from the Validation of Simplified Acute Physiology Score 3 (SAPS3) in Korean ICU (VSKI) study, which is a nationwide, multicenter, and prospective study that considered 5,063 patients from 22 ICUs in Korea over a period of 7 months. Among them, patients older than 18 years of age who were diagnosed with solid or hematologic malignancies prior to admission to the ICU were included in the present study. Results: During the study period, a total of 1,762 cancer patients were admitted to the ICUs and 833 of them were deemed eligible for analysis. Six hundred fifty-eight (79%) had solid tumors and 175 (21%) had hematologic malignancies, respectively. Respiratory problems (30.1%) was the most common reason leading to ICU admission. Patients with hematologic malignancies had higher Sequential Organ Failure Assessment (12 vs. 8, P < 0.001) and SAPS3 (71 vs. 69, P < 0.001) values and were more likely to be associated with chemotherapy, steroid therapy, and immunocompromised status versus patients with solid tumors. The use of inotropes/vasopressors, mechanical ventilation, and/or continuous renal replacement therapy was more frequently required in hematologic malignancy patients. Mortality rates in the ICU (41.7% vs. 24.6%, P < 0.001) and hospital (53.1% vs. 38.6%, P = 0.002) were higher in hematologic malignancy patients than in solid tumor patients. Conclusions: Cancer patients accounted for one-third of all patients admitted to the studied ICUs in Korea. Clinical characteristics were different according to the type of malignancy. Patients with hematologic malignancies had a worse prognosis than did patients with solid tumor. Copyright © 2018 The Korean Society of Critical Care Medicine
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Collections - 2. Clinical Science > Department of Pulmonary, Allergy, and Critical Care Medicine > 1. Journal Articles
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