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Usefulness of Autofluorescence Imaging for Estimating the Extent of Gastric Neoplastic Lesions: A Prospective Multicenter Studyopen access

Authors
Lee, Jun HaengCho, Joo YongChoi, Myung GyuKim, Joo SungChoi, Kee DonLee, Yong ChanJang, Jae YoungChun, Hoon JaiSeol, Sang Yong
Issue Date
Dec-2008
Publisher
EDITORIAL OFFICE GUT & LIVER
Keywords
Fluorescence; Imaging; Gastric cancer; Adenoma; Resection
Citation
GUT AND LIVER, v.2, no.3, pp.174 - 179
Indexed
SCIE
Journal Title
GUT AND LIVER
Volume
2
Number
3
Start Page
174
End Page
179
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/31417
DOI
10.5009/gnl.2008.2.3.174
ISSN
1976-2283
Abstract
Background/Aims: The aim of this study was to determine whether the margin of early to be detected gastric cancer (EGC) and gastric adenoma is easier to be detected with autofluorescence imaging (AFI) than with white-light endoscopy (WILE). Methods: A total of 102 lesions (48 EGCs and 54 gastric adenomas) found in 98 patients were removed endoscopically or surgically. The measured length of each pathology specimen was compared with the lengths estimated using WLE, AFI, and chromoendoscopy. Results: The lesions could be discriminated from surrounding mucosa by AFI in 86 cases (84.3%). The detection rates were similar for elevated lesions (85.1%) and flat/depressed lesions (82.9%, p=0.770). In terms of histology, the detection rate was slightly higher for adenomas (90.7%) than for cancer (77.1%, p=0.058). The estimated length was shorter than the pathologic length in 31.4% of cases when using WLE and 22.1% of cases when using AFI (p=0.168). The resection range was larger for EMR than for AFI in 24 of 80 cases (30.0%). Conclusions: WILE tends to underestimate the size of EGCs, whereas AFI tends to overestimate their size. (Gut and Liver 2008, 2:174-179)
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Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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