Ticlopidine에 의해 유발된 담즙정체간염과 진정적혈구계무형성증 1예A case of ticlopidine induced acute cholestatic hepatitis and pure red cell aplasia
- Other Titles
- A case of ticlopidine induced acute cholestatic hepatitis and pure red cell aplasia
- Authors
- 이지연; 박은범; 안재홍; 서상준; 정영걸; 김지훈; 신봉경; 양진혁; 연종은; 변관수
- Issue Date
- Mar-2008
- Publisher
- 대한간학회
- Keywords
- Ticlopidine; Pure red cell aplasia; Hepatitis, Drug-Induced; Adverse effect; 티클로피딘; 진정적혈구계무형성증; 담즙정체간염; 부작용
- Citation
- The Korean Journal of Hepatology, v.14, no.1, pp 102 - 107
- Pages
- 6
- Indexed
- KCI
- Journal Title
- The Korean Journal of Hepatology
- Volume
- 14
- Number
- 1
- Start Page
- 102
- End Page
- 107
- URI
- https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/31619
- DOI
- 10.3350/kjhep.2008.14.1.102
- ISSN
- 1226-0479
- Abstract
- Ticlopidine inhibits platelet aggregation and provides beneficial secondary prevention of cerebrovascular and coronary artery disease. Frequently reported adverse effects of ticlopidine include diarrhea, nausea, and rash. However, to our knowledge, there are only a few published reports of the simultaneous occurrence of cholestatic hepatitis and pure red cell aplasia. Here we report a patient with simultaneous severe cholestatic hepatitis and pure red cell aplasia associated with ticlopidine. Although these adverse effects are rare, periodic hematological and liver function tests are recommended after starting ticlopidine.
Ticlopidine inhibits platelet aggregation and provides beneficial secondary prevention of cerebrovascular and coronary artery disease. Frequently reported adverse effects of ticlopidine include diarrhea, nausea, and rash. However, to our knowledge, there are only a few published reports of the simultaneous occurrence of cholestatic hepatitis and pure red cell aplasia. Here we report a patient with simultaneous severe cholestatic hepatitis and pure red cell aplasia associated with ticlopidine. Although these adverse effects are rare, periodic hematological and liver function tests are recommended after starting ticlopidine.
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- Appears in
Collections - 2. Clinical Science > Department of Pathology > 1. Journal Articles
- 2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles
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