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Cited 3 time in webofscience Cited 3 time in scopus
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Minimally Invasive Gastric Electrical Stimulation Using a Newly Developed Wireless Gastrostimulator: A Pilot Animal Study

Authors
Kim, Seung HanKim, Hong BaeChun, Hoon JaiChoi, Hyuk SoonKim, Eun SunKeum, BoraSeo, Yeon SeokJeen, Yoon TaeLee, Hong SikUm, Soon HoKim, Chang Duck
Issue Date
Jul-2020
Publisher
대한소화기 기능성질환∙운동학회
Keywords
Electric stimulation; Endoscopy; Gastroparesis
Citation
Journal of Neurogastroenterology and Motility (JNM), v.26, no.3, pp.410 - 416
Indexed
SCIE
SCOPUS
KCI
Journal Title
Journal of Neurogastroenterology and Motility (JNM)
Volume
26
Number
3
Start Page
410
End Page
416
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/32987
DOI
10.5056/jnm20063
ISSN
2093-0879
Abstract
Background/Aims Gastric electrical stimulation (GES) is a feasible modality for the treatment of gastroparesis; however, the presently available device requires invasive surgical implantation for long-term stimulation and repeated surgical procedure after a period of time. This study is aimed at developing a wireless miniature GES device and testing its endoscopic insertion in animal models. Methods Endoscopic gastric implantation of the GES device was performed on 5 healthy weaner pigs under general anesthesia. We created an endoscopic submucosal pocket and inserted the gastro-electrical stimulator. In vivo gastric slow waves were recorded and measured during electrical stimulation. A multi-channel recorder, called an electrogastrogram, was used to record the gastric myoelectrical activity in the study. Results The gastric slow waves on the electrogastrogram were more consistent with GES on the gastric tissues compared to no stimulation. The frequency-to-amplitude ratio was also significantly altered after the electrical stimulation. Conclusions GES is feasible with our minimally invasive wireless device. This technique has the potential to increase utilization of GES as a treatment alternative.
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5. Others > Others(Medicine) > 1. Journal Articles
2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

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Keum, Bora
Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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