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Long-Term Clinical Outcomes of Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer: A Prospective Multicenter Cohort Study

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dc.contributor.authorKim, Sang Gyun-
dc.contributor.authorPark, Chan Mi-
dc.contributor.authorLee, Na Rae-
dc.contributor.authorKim, Jiyoung-
dc.contributor.authorLyu, Da Hyun-
dc.contributor.authorPark, Seung-Hee-
dc.contributor.authorChoi, Il Ju-
dc.contributor.authorLee, Wan Sik-
dc.contributor.authorPark, Seun Ja-
dc.contributor.authorKim, Jae Jun-
dc.contributor.authorKi, Ji Hyun-
dc.contributor.authorLim, Chul-Hyun-
dc.contributor.authorCho, Joo Young-
dc.contributor.authorKim, Gwang Ha-
dc.contributor.authorLee, Yong Chan-
dc.contributor.authorJung, Hwoon-Yong-
dc.contributor.authorLee, Jun Haeng-
dc.contributor.authorChun, Hoon Jai-
dc.contributor.authorSeol, Sang-Yong-
dc.date.available2020-11-02T07:15:19Z-
dc.date.issued2018-07-
dc.identifier.issn1976-2283-
dc.identifier.issn2005-1212-
dc.identifier.urihttps://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/3384-
dc.description.abstractBackground/Aims: Endoscopic submucosa I dissection (ESD) has been regarded as a curative treatment for early gastric cancer (EGC) in indicated cases. The aim of this study was to evaluate the nationwide long-term clinical outcomes of ESD for EGC in Korea. Methods: A prospective multicenter cohort study was performed to evaluate the long-term efficacy of ESD for EGC within pre-defined indications at 12 institutes in Korea. The cases that met the expanded criteria upon pathological review after ESD were followed for 5 years. The primary outcome was 5-year disease specific free survival. Results: Six hundred ninety-seven patients with 722 EGCs treated with ESD were prospectively enrolled and followed for 5 years. Complete resection was achieved in 81.3% of the cases, and curative resection was achieved in 86.1%. During the 5-year follow-up, the overall survival rate was 96.6%, and the disease specific free survival rate was 90.6%. Local recurrence developed in 0.9%, and metachronous tumor development occurred in 7.8%; both conditions were treated by endoscopic or surgical treatment. Distant metastasis developed in 0.5% during-follow-up. Conclusions: ESD showed excellent long-term clinical outcomes and can be accepted as a curative treatment for patients with EGC who meet the expanded criteria in final pathology studies.-
dc.format.extent9-
dc.language영어-
dc.language.isoENG-
dc.publisherEDITORIAL OFFICE GUT & LIVER-
dc.titleLong-Term Clinical Outcomes of Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer: A Prospective Multicenter Cohort Study-
dc.typeArticle-
dc.publisher.location대한민국-
dc.identifier.doi10.5009/gnl17414-
dc.identifier.scopusid2-s2.0-85047872133-
dc.identifier.wosid000436520300007-
dc.identifier.bibliographicCitationGUT AND LIVER, v.12, no.4, pp 402 - 410-
dc.citation.titleGUT AND LIVER-
dc.citation.volume12-
dc.citation.number4-
dc.citation.startPage402-
dc.citation.endPage410-
dc.type.docTypeArticle-
dc.identifier.kciidART002367557-
dc.description.isOpenAccessY-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.relation.journalResearchAreaGastroenterology & Hepatology-
dc.relation.journalWebOfScienceCategoryGastroenterology & Hepatology-
dc.subject.keywordPlusRISK-FACTORS-
dc.subject.keywordPlusRESECTION-
dc.subject.keywordAuthorSurvival-
dc.subject.keywordAuthorEndoscopic mucosal dissection-
dc.subject.keywordAuthorStomach neoplasms-
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Anam Hospital (Department of Gastroenterology and Hepatology, Anam Hospital)
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