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Cited 23 time in webofscience Cited 26 time in scopus
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Excess Comorbidity Prevalence and Cost Associated with Functional Dyspepsia in an Employed Population

Authors
Brook, Richard A.Kleinman, Nathan L.Choung, Rok SeonSmeeding, James E.Talley, Nicholas J.
Issue Date
Jan-2012
Publisher
Kluwer Academic/Plenum Publishers
Keywords
Functional dyspepsia; Comorbidities; Costs; Prevalence
Citation
Digestive Diseases and Sciences, v.57, no.1, pp 109 - 118
Pages
10
Indexed
SCI
SCIE
SCOPUS
Journal Title
Digestive Diseases and Sciences
Volume
57
Number
1
Start Page
109
End Page
118
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/35117
DOI
10.1007/s10620-011-1822-8
ISSN
0163-2116
1573-2568
Abstract
Background Limited published data exist on the associated comorbid conditions with functional dyspepsia (FD). Aims This study aimed to assess the prevalence, services, and costs related to comorbid conditions associated with FD and the risk of having FD for each comorbid condition. Methods A retrospective database analysis was undertaken using payroll data and adjudicated claims from January 1, 2001, through December 31, 2004 among >300,000 employees. Employees with FD were compared to propensity-score-matched employees without FD (controls). Outcome measures included the prevalence, costs, and utilization of health services for comorbid conditions as defined by the Agency for Healthcare Research and Quality (AHRQ) and the odds ratios of having FD from a multivariate model. Results FD employees (N = 1,669) and a 50:1 matched control cohort (N = 83,450) were compared. Compared to matched controls, FD employees were more likely to have all major diagnostic categories. Moreover, 199/261 of the AHRQ’s specific categories were more common in the FD cohort. Annual medical costs for the FD cohort were greater than for controls in 155/261 (59%) specific categories and significantly greater (P ≤ 0.05) in 76 categories (29%). Similarly, services were greater for 179/261 (69%) specific categories and significantly greater (P ≤ 0.05) in 110 categories (42%). In a multivariate model, esophageal disorders, gastritis and duodenitis, and abdominal pain were the most associated with having FD (odds ratios 3.8, 3.7, and 3.6, respectively). Only hypertension complications and disorders of the teeth and jaw were significantly negatively associated with FD. Conclusion There is unexplained excess comorbidity associated with FD which may be a major determining factor for excess healthcare services and costs.
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2. Clinical Science > Department of Gastroenterology and Hepatology > 1. Journal Articles

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