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Cited 22 time in webofscience Cited 20 time in scopus
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The Clinical Research Center for Depression Study: Baseline Characteristics of a Korean Long-Term Hospital-Based Observational Collaborative Prospective Cohort Studyopen access

Authors
Kim, Tae-SukJeong, Seung HeeKim, Jung-BumLee, Min-SooKim, Jae-MinYim, Hyeon-WooJun, Tae-Youn
Issue Date
Mar-2011
Publisher
KOREAN NEUROPSYCHIATRIC ASSOC
Keywords
Depression; Hospital-based; Longitudinal; Observational; Prospective
Citation
PSYCHIATRY INVESTIGATION, v.8, no.1, pp.1 - 8
Indexed
SCIE
SCOPUS
KCI
Journal Title
PSYCHIATRY INVESTIGATION
Volume
8
Number
1
Start Page
1
End Page
8
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/35239
DOI
10.4306/pi.2011.8.1.1
ISSN
1738-3684
Abstract
Objective The Clinical Research Center for Depression (CRESCEND) study is a 9-year observational collaborative prospective cohort study for the clinical outcomes in participants with depressive disorders in Korea. In this study, we examined the baseline characteristics of the depressive participants as the hospital-based cohort. Methods Participants were assessed using various instruments including the Clinical Global Impression scale, 17-item Hamilton Depression Rating Scale (HDRS-17), Hamilton Anxiety Rating Scale, Brief Psychiatric Rating Scale, Social and Occupational Functioning Assessment Scale, Beck Depression Inventory-Second Edition, Scale for Suicide Ideation, and World Health Organization Quality of Life assessment instruments-abbreviated version. Also, personal histories of medical and psychiatric illnesses and the rang of socio-epidemiologic and clinical data were collected from each participant. Results One thousand one hundred eighty three participants were recruited from 18 hospitals. The mean age of the participants was 47.9 +/- 15.9 year-old, 74.4% were female, 82.9% had been diagnosed of major depressive disorder, 40.9% were experiencing their first depressive episode, and 21.4% had a past history of suicide attempts. The majority (85.3%) of the participants were moderately to severely ill. The average HDRS-17 was 19.8 +/- 6.1. Significant gender differences at baseline were shown in age, education, marriage, employment, religion, and first depressive episode. Conclusion The baseline findings in the CRESCEND study showed some different characteristics of depression in Korea, suggesting a possibility of ethnic and cultural factors in depression. Psychiatry Investig 2011;8:1-8
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