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Cited 11 time in webofscience Cited 12 time in scopus
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Factors Associated with Rebleeding in Patients with Peptic Ulcer Bleeding: Analysis of the Korean Peptic Ulcer Bleeding (K-PUB) Study

Authors
Kim, Joon SungKim, Byung-WookPark, Sung MinShim, Ki-NamJeon, Seong WooKim, Sang-WookLee, Yong ChanMoon, Hee SeokLee, Si HyungJung, Woon TaeKim, Jin IlKim, Kyoung OhPark, Jong-JaeChung, Woo ChulKim, Jeong HwanBaik, Gwang HoOh, Jung HwanKim, Sun MoonKim, Hyun SooYang, Chang HeonJung, Jin TaeLim, Chul HyunSong, Hyun JooKim, Yong SikKim, Gwang HaKim, Jie-HyunChung, Jae-IlLee, Jun HaengChoi, Min HoChoi, Jong-Kyoung
Issue Date
May-2018
Publisher
거트앤리버 발행위원회
Keywords
Peptic ulcer hemorrhage; Rebleeding; Risk factors
Citation
Gut and Liver, v.12, no.3, pp.271 - 277
Indexed
SCIE
SCOPUS
KCI
Journal Title
Gut and Liver
Volume
12
Number
3
Start Page
271
End Page
277
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/3626
DOI
10.5009/gnl17138
ISSN
1976-2283
Abstract
Background/Aims Rebleeding is associated with mortality in patients with peptic ulcer bleeding (PUB), and risk stratification is important for the management of these patients. The purpose of our study was to examine the risk factors associated with rebleeding in patients with PUB. Methods The Korean Peptic Ulcer Bleeding registry is a large prospectively collected database of patients with PUB who were hospitalized between 2014 and 2015 at 28 medical centers in Korea. We examined the basic characteristics and clinical outcomes of patients in this registry. Univariate and multivariate analyses were performed to identify the factors associated with rebleeding. Results In total, 904 patients with PUB were registered, and 897 patients were analyzed. Rebleeding occurred in 7.1% of the patients (64), and the 30-day mortality was 1.0% (nine patients). According to the multivariate analysis, the risk factors for rebleeding were the presence of co-morbidities, use of multiple drugs, albumin levels, and hematemesis/hematochezia as initial presentations. Conclusions The presence of co-morbidities, use of multiple drugs, albumin levels, and initial presentations with hematemesis/hematochezia can be indicators of rebleeding in patients with PUB. The wide use of proton pump inhibitors and prompt endoscopic interventions may explain the low incidence of rebleeding and low mortality rates in Korea.
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Park, Jong Jae
Guro Hospital (Department of Gastroenterology and Hepatology, Guro Hospital)
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