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Cited 18 time in webofscience Cited 21 time in scopus
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HLA class II allele associations in Korean patients with pemphigus

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DC FieldValueLanguage
dc.contributor.authorLee, CW-
dc.contributor.authorYang, HY-
dc.contributor.authorKim, SC-
dc.contributor.authorJung, JH-
dc.contributor.authorHwang, JJ-
dc.date.available2020-12-09T12:04:52Z-
dc.date.issued1998-
dc.identifier.issn1018-8665-
dc.identifier.issn1421-9832-
dc.identifier.urihttps://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/38225-
dc.description.abstractBackground: Studies at the population level have demonstrated associations between pemphigus (pemphigus vulgaris, PV, and pemphigus foliaceus, PF) and particular HLA haplotypes, which suggests that there may be a genetic predisposition for the disease. Objective/Methods: The aim of the present study was to examine the distribution/frequency pattern of HLA class II alleles (DRB1, DQA1 and DQB1) from a group of 30 Korean patients with pemphigus (15 PV and 15 PF) by PCR amplification with sequence-specific primers. Results: In PV, the frequency of DRB1*01 allele was found to be significantly high (p(c)=0.0014); in PF, DRB1*01, DQA1*0302 and DQB1*0603 alleles showed positive associations with statistical significances (p(c)=0.0002, 0.0007 and 0.0067, respectively), when compared with those found in Korean controls. Conclusions: In this small-sample study, findings of allelic frequencies among Korean patients with pemphigus are somewhat different from those found in other populations.-
dc.format.extent4-
dc.language영어-
dc.language.isoENG-
dc.publisherKARGER-
dc.titleHLA class II allele associations in Korean patients with pemphigus-
dc.typeArticle-
dc.publisher.location스위스-
dc.identifier.doi10.1159/000018030-
dc.identifier.scopusid2-s2.0-0032406142-
dc.identifier.wosid000077797700010-
dc.identifier.bibliographicCitationDERMATOLOGY, v.197, no.4, pp 349 - 352-
dc.citation.titleDERMATOLOGY-
dc.citation.volume197-
dc.citation.number4-
dc.citation.startPage349-
dc.citation.endPage352-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaDermatology-
dc.relation.journalWebOfScienceCategoryDermatology-
dc.subject.keywordPlusFOLIACEUS FOGO-SELVAGEM-
dc.subject.keywordPlusVULGARIS-
dc.subject.keywordPlusSUSCEPTIBILITY-
dc.subject.keywordPlusHAPLOTYPES-
dc.subject.keywordPlusDRB1-
dc.subject.keywordAuthorpemphigus vulgaris-
dc.subject.keywordAuthorpemphigus foliaceus-
dc.subject.keywordAuthorHLA class II allele-
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