Association of serum mineral parameters with mortality in hemodialysis patients: Data from the korean end-stage renal disease registry
DC Field | Value | Language |
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dc.contributor.author | Kim Y. | - |
dc.contributor.author | Yoo K.D. | - |
dc.contributor.author | Kim H.J. | - |
dc.contributor.author | Koh J. | - |
dc.contributor.author | Yu Y. | - |
dc.contributor.author | Kwon Y.J. | - |
dc.contributor.author | Kim G.-H. | - |
dc.contributor.author | Yoo T.-H. | - |
dc.contributor.author | Lee J. | - |
dc.contributor.author | Jin D.-C. | - |
dc.contributor.author | Choi B.S. | - |
dc.contributor.author | Kim Y.H. | - |
dc.contributor.author | Oh K.-H. | - |
dc.date.available | 2020-11-02T07:57:42Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 2211-9132 | - |
dc.identifier.issn | 2211-9140 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/4202 | - |
dc.description.abstract | Background: We investigated the associations between mineral metabolism parameters and mortality to identify optimal targets in Korean hemodialysis patients. Methods: Among hemodialysis patients registered in the end-stage renal disease registry of the Korean Society of Nephrology between March 2012 and June 2017, those with serum calcium, phosphorus, and intact parathyroid hormone (iPTH) measured at enrollment were included. Association of serum levels of calcium, phosphorus, and iPTH with all-cause mortality was analyzed. Results: Among 21,433 enrolled patients, 3,135 (14.6%) died during 24.8 ± 14.5 months of follow-up. After multivariable adjustment, patients in the first quintile of corrected calcium were associated with lower mortality (hazard ratio [HR], 0.84; 95% confidence interval [95% CI], 0.71-0.99; P = 0.003), while those in the fifth quintile were associated with higher mortality (HR, 1.39; 95% CI, 1.20-1.61; P < 0.001) compared with those in the third quintile. For phosphorus, only the lowest quintile was significantly associated with increased mortality (HR, 1.24; 95% CI, 1.08-1.43; P = 0.003). The lowest (HR, 1.18; 95% CI, 1.02-1.36; P = 0.026) and highest quintiles of iPTH (HR, 1.24; 95% CI, 1.05-1.46; P = 0.013) were associated with increased mortality. For target counts achieved according to the Kidney Disease Outcomes Quality Initiative guideline, patients who did not achieve any mineral parameter targets hadhigher mortality than those who achieved all three targets (HR, 1.37; 95% CI, 1.12-1.67; P = 0.003). Conclusion: In Korean hemodialysis patients, high serum calcium, low phosphorus, and high and low iPTH levels were associated with increased all-cause mortality. © 2018 by The Korean Society of Nephrology. | - |
dc.format.extent | 11 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | The Korean Society of Nephrology | - |
dc.title | Association of serum mineral parameters with mortality in hemodialysis patients: Data from the korean end-stage renal disease registry | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.23876/j.krcp.2018.37.3.266 | - |
dc.identifier.scopusid | 2-s2.0-85053527043 | - |
dc.identifier.bibliographicCitation | Kidney Research and Clinical Practice, v.37, no.3, pp 266 - 276 | - |
dc.citation.title | Kidney Research and Clinical Practice | - |
dc.citation.volume | 37 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 266 | - |
dc.citation.endPage | 276 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002384368 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | esci | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordPlus | calcium | - |
dc.subject.keywordPlus | parathyroid hormone | - |
dc.subject.keywordPlus | phosphorus | - |
dc.subject.keywordPlus | adult | - |
dc.subject.keywordPlus | aged | - |
dc.subject.keywordPlus | all cause mortality | - |
dc.subject.keywordPlus | Article | - |
dc.subject.keywordPlus | calcium blood level | - |
dc.subject.keywordPlus | confidence interval | - |
dc.subject.keywordPlus | controlled study | - |
dc.subject.keywordPlus | disease registry | - |
dc.subject.keywordPlus | end stage renal disease | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | follow up | - |
dc.subject.keywordPlus | hazard ratio | - |
dc.subject.keywordPlus | hemodialysis patient | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | major clinical study | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | medical society | - |
dc.subject.keywordPlus | metabolic parameters | - |
dc.subject.keywordPlus | mineral metabolism | - |
dc.subject.keywordPlus | parathyroid hormone blood level | - |
dc.subject.keywordPlus | phosphate blood level | - |
dc.subject.keywordPlus | practice guideline | - |
dc.subject.keywordPlus | priority journal | - |
dc.subject.keywordPlus | retrospective study | - |
dc.subject.keywordPlus | South Korean | - |
dc.subject.keywordAuthor | Calcium | - |
dc.subject.keywordAuthor | Hemodialysis | - |
dc.subject.keywordAuthor | Mortality | - |
dc.subject.keywordAuthor | Parathyroid hormone | - |
dc.subject.keywordAuthor | Phosphorus | - |
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