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Cited 19 time in webofscience Cited 22 time in scopus
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Individuals with Restless Legs Syndrome Tend to have Severe Depressive Symptoms: Findings from a Community-Based Cohort Study

Authors
Cho, Chul-HyunKim, LeenLee, Heon-Jeong
Issue Date
Nov-2017
Publisher
KOREAN NEUROPSYCHIATRIC ASSOC
Keywords
Restless legs syndrome; Depressive symptom; Insomnia; Daytime sleepiness; Hematological features
Citation
PSYCHIATRY INVESTIGATION, v.14, no.6, pp 887 - 893
Pages
7
Indexed
SCIE
SSCI
SCOPUS
KCI
Journal Title
PSYCHIATRY INVESTIGATION
Volume
14
Number
6
Start Page
887
End Page
893
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/4447
DOI
10.4306/pi.2017.14.6.887
ISSN
1738-3684
1976-3026
Abstract
Restless legs syndrome (RLS) is a sensorimotor neurological disturbance causing physical and psychological distress. Here, we investigated the severity and effect of depressive symptoms in RLS among a Korean cohort population. Depressive symptoms were more prevalent in the RLS group than in the non-RLS group [>= mild depression: odds ratio (OR) = 1.95, p < 0.001; = moderate depression: OR = 6.15, p < 0.001; and = severe depression: OR = 56.54, p < 0.001], with a predominant proportion of severe depression (97%) in the RLS group. We found that difficulty falling asleep (OR = 8.16, p < 0.001), broken sleep (OR = 11.66, p = 0.001), early morning awakening (OR = 8.5, p < 0.001), and excessive daytime sleepiness (OR = 3.04, p = 0.031) were significantly frequent in individuals with severe depression in the RLS group. Red blood cell count was significantly low in individuals with severe depression in the RLS group (p = 0.041). We found that severe depression was associated with RLS, suggesting the evaluation and management of mood symptoms and sleep-related and hematological features when treating RLS.
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Lee, Heon Jeong
Anam Hospital (Department of Psychiatry, Anam Hospital)
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