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Individuals with Restless Legs Syndrome Tend to have Severe Depressive Symptoms: Findings from a Community-Based Cohort Study

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dc.contributor.authorCho, Chul-Hyun-
dc.contributor.authorKim, Leen-
dc.contributor.authorLee, Heon-Jeong-
dc.date.available2020-11-02T08:20:44Z-
dc.date.created2020-10-16-
dc.date.issued2017-11-
dc.identifier.issn1738-3684-
dc.identifier.urihttps://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/4447-
dc.description.abstractRestless legs syndrome (RLS) is a sensorimotor neurological disturbance causing physical and psychological distress. Here, we investigated the severity and effect of depressive symptoms in RLS among a Korean cohort population. Depressive symptoms were more prevalent in the RLS group than in the non-RLS group [>= mild depression: odds ratio (OR) = 1.95, p < 0.001; = moderate depression: OR = 6.15, p < 0.001; and = severe depression: OR = 56.54, p < 0.001], with a predominant proportion of severe depression (97%) in the RLS group. We found that difficulty falling asleep (OR = 8.16, p < 0.001), broken sleep (OR = 11.66, p = 0.001), early morning awakening (OR = 8.5, p < 0.001), and excessive daytime sleepiness (OR = 3.04, p = 0.031) were significantly frequent in individuals with severe depression in the RLS group. Red blood cell count was significantly low in individuals with severe depression in the RLS group (p = 0.041). We found that severe depression was associated with RLS, suggesting the evaluation and management of mood symptoms and sleep-related and hematological features when treating RLS.-
dc.language영어-
dc.publisherKOREAN NEUROPSYCHIATRIC ASSOC-
dc.subjectGENOME-WIDE ASSOCIATION-
dc.subjectIRON-DEFICIENCY ANEMIA-
dc.subjectQUALITY-OF-LIFE-
dc.subjectCIRCADIAN-RHYTHM-
dc.subjectGENERAL-POPULATION-
dc.subjectDAYTIME SLEEPINESS-
dc.subjectBLOOD-DONORS-
dc.subjectPREVALENCE-
dc.subjectDISORDERS-
dc.subjectEPIDEMIOLOGY-
dc.titleIndividuals with Restless Legs Syndrome Tend to have Severe Depressive Symptoms: Findings from a Community-Based Cohort Study-
dc.typeArticle-
dc.contributor.affiliatedAuthorCho, Chul-Hyun-
dc.contributor.affiliatedAuthorKim, Leen-
dc.contributor.affiliatedAuthorLee, Heon-Jeong-
dc.identifier.doi10.4306/pi.2017.14.6.887-
dc.identifier.scopusid2-s2.0-85034251699-
dc.identifier.wosid000415103900025-
dc.identifier.bibliographicCitationPSYCHIATRY INVESTIGATION, v.14, no.6, pp.887 - 893-
dc.relation.isPartOfPSYCHIATRY INVESTIGATION-
dc.citation.titlePSYCHIATRY INVESTIGATION-
dc.citation.volume14-
dc.citation.number6-
dc.citation.startPage887-
dc.citation.endPage893-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.identifier.kciidART002284668-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassssci-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.relation.journalResearchAreaPsychiatry-
dc.relation.journalWebOfScienceCategoryPsychiatry-
dc.subject.keywordPlusGENOME-WIDE ASSOCIATION-
dc.subject.keywordPlusIRON-DEFICIENCY ANEMIA-
dc.subject.keywordPlusQUALITY-OF-LIFE-
dc.subject.keywordPlusCIRCADIAN-RHYTHM-
dc.subject.keywordPlusGENERAL-POPULATION-
dc.subject.keywordPlusDAYTIME SLEEPINESS-
dc.subject.keywordPlusBLOOD-DONORS-
dc.subject.keywordPlusPREVALENCE-
dc.subject.keywordPlusDISORDERS-
dc.subject.keywordPlusEPIDEMIOLOGY-
dc.subject.keywordAuthorRestless legs syndrome-
dc.subject.keywordAuthorDepressive symptom-
dc.subject.keywordAuthorInsomnia-
dc.subject.keywordAuthorDaytime sleepiness-
dc.subject.keywordAuthorHematological features-
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