A prospective randomized clinical study evaluating the efficacy and compliance of oral sulfate solution and 2-L ascorbic acid plus polyethylene glycol
DC Field | Value | Language |
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dc.contributor.author | Kwon, Ki Hwan | - |
dc.contributor.author | Lee, Ji Ae | - |
dc.contributor.author | Lim, Yun Jeong | - |
dc.contributor.author | Lee, Beom Jae | - |
dc.contributor.author | Joo, Moon Kyung | - |
dc.contributor.author | Sim, Yu Ra | - |
dc.contributor.author | Choi, Wonjae | - |
dc.contributor.author | Kim, Taehyun | - |
dc.contributor.author | Kim, Ji Yoon | - |
dc.contributor.author | Cho, Ei Rie | - |
dc.contributor.author | Jeen, Yoon Tae | - |
dc.contributor.author | Park, Jong-Jae | - |
dc.date.available | 2021-02-15T01:22:01Z | - |
dc.date.issued | 2020-07 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.issn | 2005-6648 | - |
dc.identifier.uri | https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/49299 | - |
dc.description.abstract | Background/Aims: Oral sulfate solution (OSS) is an emerging cleansing agent for bowel preparation. However, data comparing OSS to other conventional bowel preparations in Asian patients are limited. Therefore, the objective of this study was to compare the efficacy and tolerability of OSS to ascorbic acid plus polyethylene glycol (AA + PEG) in Asian patients. Methods: This was a prospective, randomized, parallel, investigator-blind study performed in two university hospitals in Korea. Bowel preparation efficacy was evaluated using both the Ottawa Bowel Preparation Scale (OBPS) and Boston Bowel Preparation Scale (BBPS). Results: Among 173 patients, 86 received OSS while 87 received AA + PEG for bowel preparation. Total OBPS score was 2.80 +/- 2.48 in the OSS group and 4.49 +/- 3.08 in the AA + PEG group, indicating significantly (p < 0.001) better efficacy with OSS. Total BBPS was higher in the OSS group (7.43 +/- 1.49 vs. 6.51 +/- 1.76, p < 0.001), indicating superior bowel preparation quality with OSS. Preparation-related adverse events were generally acceptable. Patients receiving OSS had more nausea (1.92 +/- 0.94 vs. 1.54 +/- 0.76, p = 0.004) and abdominal cramping (1.45 +/- 0.78 vs. 1.17 +/- 0.51, p = 0.006) than those receiving AA + PEG. However, overall satisfaction and taste were similar between the two groups. Conclusions: OSS had a non-inferior bowel cleansing efficacy than AA + PEG regardless of colon segment. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한내과학회 | - |
dc.title | A prospective randomized clinical study evaluating the efficacy and compliance of oral sulfate solution and 2-L ascorbic acid plus polyethylene glycol | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.3904/kjim.2017.275 | - |
dc.identifier.scopusid | 2-s2.0-85088155268 | - |
dc.identifier.wosid | 000546357400016 | - |
dc.identifier.bibliographicCitation | The Korean Journal of Internal Medicine, v.35, no.4, pp 873 - 880 | - |
dc.citation.title | The Korean Journal of Internal Medicine | - |
dc.citation.volume | 35 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 873 | - |
dc.citation.endPage | 880 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002602951 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | ADENOMA DETECTION RATE | - |
dc.subject.keywordPlus | BOWEL PREPARATION | - |
dc.subject.keywordPlus | QUALITY INDICATORS | - |
dc.subject.keywordPlus | REDUCED-VOLUME | - |
dc.subject.keywordPlus | STANDARD PEG | - |
dc.subject.keywordPlus | COLONOSCOPY | - |
dc.subject.keywordPlus | SUPERIOR | - |
dc.subject.keywordPlus | TRIAL | - |
dc.subject.keywordAuthor | Ascorbic acid | - |
dc.subject.keywordAuthor | Bowel preparation | - |
dc.subject.keywordAuthor | Colonoscopy | - |
dc.subject.keywordAuthor | Oral sulfate solution | - |
dc.subject.keywordAuthor | Polyethylene glycols | - |
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