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Cited 11 time in webofscience Cited 11 time in scopus
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Mechanical Bowel Preparation Does Not Affect Clinical Severity of Anastomotic Leakage in Rectal Cancer Surgery

Authors
Ji, Woong BaeHahn, Koo YongKwak, Jung MyunKang, Dong WooBaek, Se JinKim, JinKim, Seon Hahn
Issue Date
May-2017
Publisher
SPRINGER
Citation
WORLD JOURNAL OF SURGERY, v.41, no.5, pp.1366 - 1374
Indexed
SCIE
SCOPUS
Journal Title
WORLD JOURNAL OF SURGERY
Volume
41
Number
5
Start Page
1366
End Page
1374
URI
https://scholarworks.korea.ac.kr/kumedicine/handle/2020.sw.kumedicine/5011
DOI
10.1007/s00268-016-3839-9
ISSN
0364-2313
Abstract
Background Previous multicenter randomized trials demonstrated that omitting mechanical bowel preparation (MBP) did not increase anastomotic leakage rates or other infectious complications. However, the most serious concern regarding the omission of MBP is ongoing fecal peritonitis after anastomotic leakage occurs. The aim of this study was to compare the clinical manifestations and severity of anastomotic leakage between patients who underwent MBP and those who did not. Methods This study was a single-center retrospective review of a prospectively maintained database. From January 2006 to September 2013, 1369 patients who underwent elective rectal cancer resection with primary anastomosis were identified and analyzed. Results Anastomotic leakage rates were not significantly different between patients who did not undergo MBP (77/831, 9.27%) and those who did (42/538, 7.81%). However, a significantly lower rate of clinical leakage requiring surgical exploration was observed in the leakage without MBP group (30/77, 39.0%) compared with the leakage with MBP group (30/42, 71.4%) (P = 0.001). There were no significant differences in the clinical severity of anastomotic leakage as assessed by the length of hospital stay, time to resuming a normal diet, length of antibiotic use, ileus rate, transfusion rate, ICU admission rate, and mortality rate between the leakage without MBP and leakage with MBP groups. Conclusion MBP was not found to affect the clinical severity of anastomotic leakage in elective rectal cancer surgery.
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Ji, Woong Bae
안산병원 (Department of Colon and Rectal Surgery, Ansan Hospital)
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