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Protective effects of alpha-lipoic acid on hair cell damage in diabetic zebrafish model
- Authors
- Kim, Eunmi; Lee, Dong-Won; Park, Hae-Chul; Kim, Dong Hwee
- Issue Date
- Sep-2021
- Publisher
- ELSEVIER
- Keywords
- Diabetes mellitus; Pancreatic beta-cell; Hair cell; Alpha-lipoic acid; Zebrafish
- Citation
- MOLECULAR GENETICS AND METABOLISM REPORTS, v.28
- Indexed
- SCIE
SCOPUS
- Journal Title
- MOLECULAR GENETICS AND METABOLISM REPORTS
- Volume
- 28
- ISSN
- 2214-4269
2214-4269
- Abstract
- Hearing impairment is one of the complications in diabetes mellitus; however, there are very few therapeutic studies on it. In this study, we investigated the protective effect of alpha-lipoic acid (ALA) on hearing loss in diabetic transgenic zebrafish and confirmed that ALA protects the loss of hair cells (HCs) caused by hyperglycemia. The data indicated that ALA has a protective effect on the damage to HCs in diabetic zebrafish.
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Related Researcher
- Park, Hae Chul
- Graduate School (Biomedical Research Center)